Comparison of mental stress-induced myocardial ischemia in coronary artery disease patients with versus without left ventricular dysfunction
Comparison of mental stress-induced myocardial ischemia in coronary artery disease patients with versus without left ventricular dysfunction
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DOI：
10.1016/j.amjcard.2004.09.027
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发表时间：
2005-02-01
影响因子：
2.8
通讯作者：
Gottdiener, JS
中科院分区：
文献类型：
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作者：
Akinboboye, O;Krantz, DS;Gottdiener, JS
为探讨冠心病及左心室(LV)功能正常患者与IV功能受损患者对心肌缺血的易感性，我们对58例冠心病患者进行了检查，其中IV功能正常(射血分数大于或等于50%)22例，轻至中度IV功能障碍(射血分数30%~50%)16例，重度LV功能障碍(射血分数小于或等于30%)20例。缺血的评估是基于局部静息和负荷心肌灌注的总和差值，并定义为总和差值。在三组可比的双倍乘积中，严重左心功能不全的患者(50%)比左心功能正常的患者(9%；P
To examine the susceptibility to myocardial ischemia with mental stress in patients who have coronary artery disease and normal left ventricular (LV) function versus those who have impaired IV function, we examined 58 patients who had coronary artery disease, including 22 who had normal IV function (ejection fraction greater than or equal to50%), 16 who had mild to moderate IV dysfunction (ejection fraction 30% to 50%), and 20 who had severe LV dysfunction (ejection fraction :less than or equal to30%) and underwent bicycle and mental stress testing with myocardial perfusion scintigraphy on consecutive days in random order. Ischemia was assessed based on summed difference scores in regional rest versus stress myocardial perfusion and defined as a summed difference score >3. At comparable double products across the 3 groups, ischemia was induced with mental stress more frequently in patients who had severe LV dysfunction (50%) than in those who had normal LV function (9%; p