Sequence Analysis for Assessing Potential Allergenicity
Sequence Analysis for Assessing Potential Allergenicity
复制标题
用于评估潜在过敏性的序列分析
DOI：
10.1111/j.1749-6632.2002.tb04134.x
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发表时间：
2002
影响因子：
5.2
通讯作者：
S. Gendel
中科院分区：
文献类型：
--
作者：
S. Gendel
摘要：序列分析在评估转基因食品中使用的蛋白质的潜在过敏性方面发挥着重要作用，特别是对于以前不属于食品供应的蛋白质。序列比较用于指示与现有过敏原的潜在意外交叉反应，并评估产生新敏感性的潜力。尽管使用序列分析的概念很简单，但实施准确且完整的生物信息学分析可能很复杂。需要考虑几个因素，包括序列数据库的设计和内容、分析策略以及评估结果的标准。
Abstract: Sequence analysis plays an important role in assessing the potential allergenicity of proteins used in transgenic foods, particularly for proteins that have not previously been part of the food supply. Sequence comparisons are used to indicate potential unexpected cross reactivity to existing allergens and to assess the potential for developing new sensitivities. Although the concept of using sequence analysis is straightforward, implementing a bioinformatic analysis that is accurate and complete can be complex. Several factors need to be considered, including the design and content of the sequence database, the analysis strategy, and the criteria for evaluating the results.
影响因子：
3.9
作者：
Stanley, JS;King, N;Bannon, GA
通讯作者：
Bannon, GA