Surface tension-surface area curves calculated from pressure-volume loops.
Surface tension-surface area curves calculated from pressure-volume loops.
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根据压力-体积环计算的表面张力-表面积曲线。
DOI：
10.1152/jappl.1982.53.6.1512
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Wilson,TA
中科院分区：
文献类型：
--
作者：
Wilson,TA
使用能量分析和文献中有关表面积、反冲压力和肺容积之间关系的数据来计算与压力-容积环相对应的表面张力-表面积曲线。能量分析已在前面描述过（J. Appl. Physiol.: Respirat. Environ. Movement Physiol. 50: 921–926, 1981）。它基于这样的假设：肺的组织结构构成保守的机械系统，因此压力-体积滞后主要是表面张力-表面积滞后的结果。与以前根据反冲压力计算表面张力的方法不同，该方法不依赖于这样的假设：在相同肺体积下，充满空气的肺中反冲的组织分量与充满盐水的肺的反冲压力相同。随着表面积沿着压力-体积曲线的放气边减小，表面张力的计算值减小到小于 2 dyn/cm。表面张力随着充气臂上的表面积急剧增加，达到略低于 30 dyn/cm 的极限值。表面张力-表面积曲线的形状与之前方法计算的曲线形状不同，与从肺中提取的液体的表面张力平衡获得的形状相似。
An energy analysis and data from the literature on the relation among surface area, recoil pressure, and lung volume are used to calculate the surface tension-surface area curves corresponding to pressure-volume loops. The energy analysis has been described earlier (J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 50: 921–926, 1981). It is based on the assumption that the tissue structure of the lung constitutes a conservative mechanical system and hence that pressure-volume hysteresis is primarily a result of surface tension-surface area hysteresis. Unlike previous methods of calculating surface tension from recoil pressure, this method does not rely on the assumption that the tissue component of recoil in the air-filled lung is the same as recoil pressure of the saline-filled lung at the same lung volume. The calculated values of surface tension decrease to less than 2 dyn/cm as surface area decreases along the deflation limb of the pressure-volume curve. Surface tension increases very steeply with surface area on the inflation limbs, reaching a limiting value of just under 30 dyn/cm. The shape of the surface tension-surface area curves, unlike the shape of the curves calculated by previous methods, is similar to the shape obtained on surface tension balances for fluid extracted from lungs.