In the absence of periosteum, transplanted fetal and neonatal rat coronal sutures resist osseous obliteration.
In the absence of periosteum, transplanted fetal and neonatal rat coronal sutures resist osseous obliteration.
复制标题
在没有骨膜的情况下，移植的胎儿和新生大鼠冠状缝线可抵抗骨闭塞。
DOI：
10.1097/00001665-199411000-00012
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Ogle,RC
中科院分区：
文献类型：
--
作者：
Opperman,LA;Persing,JA;Sheen,R;Ogle,RC
正常的颅面发育依赖于颅顶在缝合处的生长而扩大。不适当的缝合发展会导致颅面生长模式的全局性破坏。硬脑膜和缝线基质之间的组织相互作用在颅缝的表型维持中起着关键作用。然而，骨膜在这一过程中的作用仍然报道不足，也存在争议。为了研究骨膜在维持冠状缝合通畅中的作用，将胎鼠和新生大鼠冠状缝线移植到成年大鼠顶骨手术造成的缺损处。在供体骨膜和宿主骨膜存在和缺失的情况下，检查这些缝合线在宿主环境中的存活能力。这项研究证实，与去除硬脑膜不同，同时去除宿主骨膜和移植骨膜并不会导致胎儿或新生儿缝线的破坏。因此，就影响缝合通畅性而言，骨膜和硬脑膜是不同的组织。
Normal craniofacial development depends on expansion of the cranial vault by growth at the sutures. Inappropriate development of the sutures leads to global disruption of patterns of craniofacial growth. Tissue interactions between dura mater and suture matrix play a critical role in the phenotypic maintenance of cranial sutures. However, the function of the periosteum in this process remains under-reported and controversial. To examine the contribution of periosteum in maintaining the patency of coronal sutures, fetal and neonatal rat coronal sutures were transplanted to surgically created defects in adult rat host parietal bones. These sutures were examined for their ability to persist in the host milieu in the presence and absence of both donor and host periosteum. This study established that removal of both host and transplant periosteum, unlike removal of dura mater, did not lead to obliteration of either fetal or neonatal sutures. Thus, periosteum and dura mater are nonequivalent tissues with respect to influence on suture patency.