Converging patterns of inputs from oral structures in the postcentral somatosensory cortex of conscious macaque monkeys
Converging patterns of inputs from oral structures in the postcentral somatosensory cortex of conscious macaque monkeys
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DOI：
10.1007/s00221-004-1869-2
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发表时间：
2004-03
影响因子：
2
通讯作者：
Takashi Toda;M. Taoka
中科院分区：
文献类型：
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作者：
Takashi Toda;M. Taoka
在有意识的日本猴的中央后回的口腔区域记录单个神经元的活动。在分离的5,756个神经元中，在3b区的1,502个神经元、1区的970个神经元和2区的1,461个神经元中识别出感受野（RF）和子模态。从区域3b向区域2（双侧整合）尾侧移动后，具有双侧RF的神经元的相对发生率逐渐增加。共有276个神经元具有覆盖三叉神经的上颌和下颌分支的双颌RF，例如上唇和下唇、上下牙齿、腭和舌或其组合。也有一种趋势，神经元的相对发病率与双颌射频增加整个中央后回，但在区域2（双颌整合）的突然变化。共有382个神经元的复合射频覆盖超过一个的五个口腔结构：唇，颊粘膜，牙齿/牙龈，舌头，和腭。与复合RF的神经元的相对发病率显着高于2区3b和1（结构间整合）。这些结果表明，从口腔结构的输入的收敛收益在一个层次的方式在中央后回，但主要是在2区的双颌和结构间的整合。在所有三个区域中，与牙齿/牙龈或腭相关的神经元中具有复合RF的神经元的相对发生率高于与舌或唇相关的神经元。我们解释这意味着口腔结构之间的解剖或功能差异可能反映在口腔表征的会聚模式中。
Single neuronal activities were recorded in the oral region of the postcentral gyrus in conscious Japanese monkeys. Among 5,756 neurons isolated, receptive fields (RFs) and submodalities were identified in 1,502 neurons in area 3b, 970 in area 1, and 1,461 in area 2. The relative incidence of neurons that had bilateral RFs increased gradually upon moving caudally from area 3b to area 2 (bilateral integration). A total of 276 neurons had bimaxillary RFs covering both the maxillary and mandibular divisions of the trigeminal nerve, such as the upper and lower lips, upper and lower teeth, palate and tongue, or combinations thereof. There was also a tendency for the relative incidence of neurons with bimaxillary RFs to increase across the postcentral gyrus but with an abrupt change in area 2 (bimaxillary integration). A total of 382 neurons had composite RFs covering more than one of five oral structures: lip, cheek mucosa, teeth/gingiva, tongue, and palate. The relative incidence of neurons with composite RFs was significantly higher in area 2 than in areas 3b and 1 (interstructural integration). These results indicate that the convergence of inputs from oral structures proceeds in a hierarchical manner across the postcentral gyrus, but chiefly in area 2 for the bimaxillary and interstructural integrations. The relative incidence of neurons with composite RFs was higher among neurons associated with the teeth/gingiva or palate than among neurons associated with the tongue or lip in all three areas. We interpret this to mean that anatomical or functional differences between oral structures might be reflected in the converging patterns in the oral representation.