Clinical performance of digital cervicography and cytology for cervical cancer screening in HIV-infected women in Lusaka, Zambia.
Clinical performance of digital cervicography and cytology for cervical cancer screening in HIV-infected women in Lusaka, Zambia.
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赞比亚卢萨卡的HIV感染妇女的宫颈癌筛查数字宫颈造影和细胞学的临床性能。
DOI：
10.1097/qai.0000000000000270
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发表时间：
2014-10-01
期刊：
影响因子：
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通讯作者：
Chibwesha CJ
中科院分区：
文献类型：
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作者：
Bateman AC;Parham GP;Sahasrabuddhe VV;Mwanahamuntu MH;Kapambwe S;Katundu K;Nkole T;Mulundika J;Pfaendler KS;Hicks ML;Shibemba A;Vermund SH;Stringer JS;Chibwesha CJ
虽然关于 VIA 在 HIV 感染女性中的临床表现的文献越来越多，但据我们所知，没有人研究过数字宫颈造影增强 VIA 的效果。我们评估了宫颈造影和细胞学的临床表现，以检测 2 级或更严重的宫颈上皮内瘤变。宫颈造影的敏感性和特异性分别为 84%（95% 置信区间 [CI]：72%–91%）和 58%（95%CI：52%–64%）。对于高级鳞状上皮内病变或更差的细胞学截止值，敏感性和特异性分别为 61% (95%CI: 48%–72%) 和 58% (95%CI: 52%–64%)。在我们的研究中，对于感染艾滋病毒的女性来说，宫颈造影似乎与细胞学检查一样有效。
While there is a growing literature on the clinical performance of VIA in HIV-infected women, to our knowledge none have studied VIA enhanced by digital cervicography. We estimated clinical performance of cervicography and cytology to detect cervical intraepithelial neoplasia grade 2 or worse. Sensitivity and specificity of cervicography were 84% (95% confidence interval [CI]: 72%–91%) and 58% (95%CI: 52%–64%). At the high-grade squamous intraepithelial lesion or worse cutoff for cytology, sensitivity and specificity were 61% (95%CI: 48%–72%) and 58% (95%CI: 52%–64%). In our study, cervicography appears to be as good as cytology in HIV-infected women.