CORONARY-ARTERY CALIBER IN NORMAL-CHILDREN AND PATIENTS WITH KAWASAKI-DISEASE BUT WITHOUT ANEURYSMS - AN ECHOCARDIOGRAPHIC AND ANGIOGRAPHIC STUDY
CORONARY-ARTERY CALIBER IN NORMAL-CHILDREN AND PATIENTS WITH KAWASAKI-DISEASE BUT WITHOUT ANEURYSMS - AN ECHOCARDIOGRAPHIC AND ANGIOGRAPHIC STUDY
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DOI：
10.1016/s0735-1097(86)80390-4
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发表时间：
1986-11-01
影响因子：
24
通讯作者：
KAPLAN, S
中科院分区：
文献类型：
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作者：
ARJUNAN, K;DANIELS, SR;KAPLAN, S
共有110名3个月至16岁的儿童接受了冠状动脉二维超声心动图检查。对42例正常人和68例川崎病患者进行评价。68例川崎病患者均行选择性冠状动脉造影。本研究的目的是：1)利用超声心动图对婴儿、幼儿和儿童的左、右近端冠状动脉的直径和形状进行正常描绘；2)比较无明显动脉瘤的川崎病患者与正常儿童冠状动脉的尺寸和形状；3)制定标准，以区分川崎病患者的大而正常的冠状动脉和真正的动脉瘤。在正常受试者和川崎病患者中，冠状动脉的直径从开口到远端10mm变化不大，大小从婴儿2mm到青少年5mm不等。男女受试者之间无显著差异。区分无动脉瘤的大而正常冠状动脉与有动脉瘤的冠状动脉的特征是其口径均匀。对侧冠状动脉口径一般处于正常的下限。使用高分辨率二维超声心动图可以准确评估婴儿和儿童的近端冠状动脉，并且可以对随时间的细微变化进行顺序评估。
A total of 110 children aged 3 months to 16 years underwent two-dimensional echocardiography of the coronary arteries. Forty-two normal subjects and 68 patients with Kawasaki disease were evaluated. All 68 patients with Kawasaki disease underwent selective coronary arteriography. The objects of this study were to 1) develop a normal profile of the proximal left and right coronary arteries as to caliber and shape in infants, toddlers and children using echocardiography; 2) compare the dimensions and shape of the coronary arteries of patients with Kawasaki disease but no obvious aneurysms with those of the coronary arteries of normal children; and 3) develop criteria that would permit distinguishing a large but normal coronary artery from a true aneurysm in patients with Kawasaki disease. In the normal subjects and patients with Kawasaki disease, the caliber of the coronary arteries showed little variability from the ostium to 10 mm distally, and ranged in size from 2 mm in infants to 5 mm in teenagers. There was no significant difference between male and female subjects. The feature that distinguished the large but normal coronary artery without aneurysm from that with an aneurysm was its uniformity of caliber. Also, the caliber of the opposite coronary artery was generally at the lower limits of normal. It appears that the proximal coronary arteries of infants and children can be accurately assessed using high resolution two-dimensional echocardiography, and that sequential evaluation of subtle changes over time may be performed.