Neuropsychological characteristics of young children from high-density alcoholism families:: A three-year follow-up
Neuropsychological characteristics of young children from high-density alcoholism families:: A three-year follow-up
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DOI：
10.15288/jsa.2003.64.195
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发表时间：
2003-03-01
期刊：
影响因子：
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通讯作者：
Cadaveira, F
中科院分区：
文献类型：
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作者：
Corral, M;Holguín, SR;Cadaveira, F
目的：我们对一组来自高密度酒精中毒家庭的幼儿（HD儿童）进行了一项随访研究，他们在大约3.5年前首次接受评估，目的是评估语言广度和视觉空间能力（HD和对照组儿童在第一次评估时存在显著差异）以及其他神经心理学指标。方法：在第二次评估中，对22名男孩和女孩进行了评估。他们在家庭收入和父母的教育水平方面是相似的。12名HD儿童有一个酗酒的父亲和至少两个其他酗酒的亲戚，而10名C儿童在第一代或第二代都没有酗酒的家族史。建立了一个神经心理电池标准化的任务，以测量注意，记忆，视觉空间和执行功能。结果如下：分析显示，在数字广度子测试中，高密度儿童的表现增加，直到达到对照组儿童的表现，在威斯康星州卡片分类测试（WCST）中，高密度儿童没有表现出与C儿童相同的改善。在WCST的持续反应中也观察到了组因素的主效应。结论：高密度的儿童达到相同的水平的性能控制儿童的语言广度，但组之间的差异随着时间的推移增加执行功能的WCST测量。这些结果被认为是在发展迟缓假说的背景下。然而，样本量小意味着需要进一步的研究来证实我们的发现。
Objective: We performed a follow-up study of a group of young children from high-density alcoholism families (HD children), who were first assessed about 3.5 years ago, with the aim of evaluating verbal span and visuospatial abilities (which differed significantly between HD and control [C] children at the first assessment), as well as other neuropsychological measures. Method: In this second assessment, 22 boys and girls were evaluated. They were comparable in family income and parents' level of education. The 12 HD children had an alcoholic father and at least two other alcoholic relatives, whereas the 10 C children had no family history of alcoholism in either the first or second generation. A neuropsychological battery was set up with standardized tasks to measure attention, memory, visuospatial and executive functions. Results: Analysis revealed significant Group x Assessment interactions in the digit span subtest where high-density children increased their performance until it reached that of the control children, and in the Wisconsin Card Sorting Test (WCST) where high-density children did not show the same improvement as the C children with maturation. A main effect was also observed for group factor in perseverative responses of the WCST. Conclusions: High-density children attain the same level of performance as control children for verbal span, but differences between groups increase over time for executive functioning as measured by the WCST. These results are considered in the context of the developmental delay hypothesis. The small sample size, however, means further studies will be necessary to confirm our findings.