Super tough double network hydrogels and their application as biomaterials
Super tough double network hydrogels and their application as biomaterials
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DOI：
10.1016/j.polymer.2012.03.013
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发表时间：
2012-04-17
期刊：
影响因子：
4.6
通讯作者：
Gong, Jian Ping
中科院分区：
文献类型：
--
作者：
Haque, Md. Anamul;Kurokawa, Takayuki;Gong, Jian Ping
双网络（ON）技术，由作者的小组开发，提供了一个创新的和通用的通道，以制造与橡胶相媲美的超高韧性的水凝胶。ON水凝胶优异的力学性能来源于两种具有不同结构的网络的特定组合。第一脆性网络充当牺牲键，其断裂成小簇以有效地将裂纹尖端周围的应力分散到周围的损伤区中，而第二韧性聚合物链充当隐藏长度，其广泛延伸以维持大变形。基于ON水凝胶的原理，作者的小组最近开发了几种新的系统和技术，这极大地扩展了ON技术的实际可及性。ON原理和ON凝胶已经在软物质界引起了广泛的关注。受ON原理的启发，许多研究小组也设计和开发了一些创新的水凝胶，其机械强度和韧性得到了大幅提高。通过ON技术制备的坚韧水凝胶具有良好的生物相容性和低摩擦阻力，在工业和医学领域具有广阔的应用前景，特别是在人工软骨等承重人工软组织方面。在这篇专题文章中，我们解决了ON凝胶的主要概念和增韧机制，然后我们描述了一些最近的新的水凝胶系统的基础上ON的概念，最后讨论了ON凝胶作为软生物材料的适用性。(C)2012爱思唯尔有限公司保留所有权利。
The double network (ON) technique, developed by authors' group, provides an innovative and universal pass way to fabricate hydrogels with super high toughness comparable to rubbers. The excellent mechanical performances of ON hydrogels originate from the specific combination of two networks with contrasting structures. The first brittle network serves as sacrificial bonds, which breaks into small clusters to efficiently disperse the stress around the crack tip into the surrounding damage zone, while the second ductile polymer chains act as hidden length, which extends extensively to sustain large deformation. Based on the principle of ON hydrogel, the author's group recently has developed several novel systems and techniques, which has greatly expanded the practical accessibility of ON technique for practical use. The ON principle and the ON gel have already attracted much attention in the soft matter community. Inspired by the ON principle, many research groups have also designed and developed some innovative hydrogels with large enhancement in their mechanical strength and toughness. Some tough hydrogels fabricated by the ON technique also exhibit good biocompatibility and low friction resistance with promising prospective in industrial and medicine fields, especially for load-bearing artificial soft tissues such as artificial cartilage. In this feature article, we address the major concept and toughening mechanism of ON gel, then we describe some recent novel hydrogel systems based on the ON concept, and finally the applicability of ON gel as soft biomaterials is discussed. (C) 2012 Elsevier Ltd. All rights reserved.