Investigation of air pollution and noise on progression of thoracic aortic calcification: results of the Heinz Nixdorf Recall Study
Investigation of air pollution and noise on progression of thoracic aortic calcification: results of the Heinz Nixdorf Recall Study
复制标题
DOI：
10.1177/2047487319854818
复制
发表时间：
2020-06-01
影响因子：
8.3
通讯作者：
Kaelsch, Hagen
中科院分区：
文献类型：
--
作者：
Hennig, Frauke;Moebus, Susanne;Kaelsch, Hagen
目的空气污染和噪声是亚临床动脉粥样硬化的潜在危险因素。纵向分析，特别是关于这些环境因素的相互作用的分析，是稀缺和不一致的。因此，我们调查了与交通相关的空气污染和噪声的长期暴露与胸主动脉钙化的发展和进展，胸主动脉钙化是亚临床动脉粥样硬化的标志。方法我们使用德国Heinz Nixdorf Recall队列研究的基线(2000-2003)和随访(2006-2008)数据，包括4814名中年人。基于住宅的空气污染(PM2.5(空气动力学直径
AimsAir pollution and noise are potential risk factors for subclinical atherosclerosis. Longitudinal analyses, especially on the interplay of these environmental factors, are scarce and inconsistent. Hence we investigated long-term traffic-related exposure to air pollution and noise with the development and progression of thoracic aortic calcification, a marker of subclinical atherosclerosis.MethodsWe used baseline (2000-2003) and follow-up (2006-2008) data from the German Heinz Nixdorf Recall cohort study, including 4814 middle-aged adults. Residence-based air pollution (PM2.5 (aerodynamic diameter