Relation of lipids, weight and physical activity to incidence of coronary heart disease: the Puerto Rico heart study.
Relation of lipids, weight and physical activity to incidence of coronary heart disease: the Puerto Rico heart study.
复制标题
血脂、体重和体力活动与冠心病发病率的关系：波多黎各心脏研究。
DOI：
10.1016/0002-9149(78)90637-9
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
Paul D. Sorlie
中科院分区：
文献类型：
--
作者：
R. Costas;M. García;E. Nazario;Paul D. Sorlie
冠心病的2 - 1 - 2年的发病率进行了检查，在队列中的8171名城市和农村男性45至64岁的参与波多黎各心脏计划的前期血清胆固醇和空腹甘油三酯水平，体力活动状态和相对体重。在这一冠心病发病率较低的人群中，城市和农村人群的冠心病危险性均与血清胆固醇相关，但这一趋势仅在城市人群中有统计学意义。无论是城市还是农村人口，血清甘油三酯水平与冠心病的发病率都没有实质性或统计学显著性相关。相对体重与血清甘油三酯和血清胆固醇水平之间存在相关性。尽管城市和农村人群之间冠心病发病率存在微小差异，但城市男性的血清胆固醇、甘油三酯和相对体重均显著高于农村男性。只有农村男子的体育活动水平较高。多变量分析，进行整理出这些相互关联的变量的净效应，揭示了血清胆固醇与冠心病的风险，即使所有变量都考虑在内。仅在城市男性中，低水平的体力活动与冠心病的发病率显著相关（P< 0.05）。超重，这是与较高的血脂值和较少的体力活动，是不相关的冠心病的发展，无论是在城市或农村队列。
The 2 1 2 year incidence of coronary heart disease was examined in relation to antecedent serum cholesterol and fasting triglyceride levels, physical activity status and relative weight in a cohort of 8, 171 urban and rural men 45 to 64 years old participating in the Puerto Rico Heart Program. In this population with a low incidence rate of coronary heart disease, risk of coronary disease was related to serum cholesterol in both urban and rural groups, but this trend was statistically significant only in the urban population. Neither the urban nor the rural population showed a substantial or statistically significant association of serum triglyceride levels with incidence of coronary heart disease. Correlations among relative weight and serum triglyceride and serum cholesterol levels were noted. Despite small differences in incidence of coronary heart disease between urban and rural groups, values for serum cholesterol, triglycerides and relative weight were all significantly higher in the urban men. Only physical activity levels were higher in the rural men. Multivariate analysis, performed to sort out the net effects of these interrelated variables, revealed that serum cholesterol is related to the risk of coronary heart disease even when all variables are taken into account. Low levels of physical activity were significantly associated with a greater incidence of coronary heart disease only in urban men (P< 0.05). Overweight, which was associated with higher lipid values and less physical activity, was not related to the development of coronary heart disease in either the urban or the rural cohort.