A Comparative Study of White Light Endoscopy, Chromoendoscopy and Magnifying Endoscopy with Narrow Band Imaging in the Diagnosis of Early Gastric Cancer after Helicobacter pylori Eradication
A Comparative Study of White Light Endoscopy, Chromoendoscopy and Magnifying Endoscopy with Narrow Band Imaging in the Diagnosis of Early Gastric Cancer after Helicobacter pylori Eradication
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DOI：
10.15403/jgld.2014.1121.264.hpy
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发表时间：
2017-12-01
影响因子：
2.1
通讯作者：
Ohmiya, Naoki
中科院分区：
文献类型：
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作者：
Horiguchi, Noriyuki;Tahara, Tomomitsu;Ohmiya, Naoki
背景与目的：根除H. pylori后发现的早期胃癌（EGC）通常在肿瘤组织和/或肿瘤表面分化上有非肿瘤上皮，这可能会混淆内镜和组织学诊断。我们研究了使用传统白光内窥镜检查 (WLE)、使用靛蓝胭脂红的色素内窥镜检查 (CE) 和窄带成像放大内窥镜检查 (ME-NBI) 对有或没有既往幽门螺杆菌根除治疗史的 EGC 患者的 EGC 诊断可靠性。方法：在成功根除幽门螺杆菌后诊断的 71 个 EGC 病灶（根除组）和115 个当前幽门螺杆菌感染的 EGC 病变（对照组）。结果：使用所有三种方式，根除组中 EGC 的诊断可靠性低于对照组。特别是，根除组中CE的诊断准确率尤其低于对照组（WLE：74.6% vs. 86.1%，P=0.05；CE：64.8% vs. 91.3%，P
Background & Aim: Early-stage gastric cancer (EGC) found after H. pylori eradication often has non-tumorous epithelium on the tumorous tissue and/or surface differentiation of tumors, which may confuse endoscopic and histologic diagnosis. We investigated the diagnostic reliability of EGC using conventional white light endoscopy (WLE), chromoendoscopy (CE) using indigo carmine, and magnifying endoscopy with narrow band imaging (ME-NBI) in patients with EGC with or without history of prior H. pylori eradication therapy.Methods: Diagnostic reliability of EGC by using the WLE, CE and ME-NBI was investigated in 71 EGC lesions diagnosed after successful H. pylori eradication (eradication group) and 115 EGC lesions with current H. pylori infection (control group).Results: Diagnostic reliability of EGC was lower in the eradication group than in the control group using all three modalities. In particular, the diagnostic accuracy of CE in the eradication group was especially lower compared to that of the control group (WLE: 74.6% vs. 86.1%, P=0.05; CE: 64.8% vs. 91.3%, P