Predictors of decline in MMSE scores among older Mexican Americans

Predictors of decline in MMSE scores among older Mexican Americans
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DOI:
10.1093/gerona/57.3.m181
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发表时间:
2002-03-01
影响因子:
5.1
通讯作者:
Markides, KS
Markides, KS
中科院分区:
医学1区
文献类型:
--
作者:
Nguyen, HT;Black, SA;Markides, KS

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背景资料。这项分析的目的是检验社会人口学变量和健康相关疾病与墨西哥裔美国老年人认知功能5年来下降的关系。采用简易智力状态检查(MMSE)对1759名受试者在1993/1994年和1998/1999年进行了认知功能评估。认知能力下降由两套标准来定义:(1)在随访时下降到17分或低于MMSE,以及(2)下降至少3分。MMSE得分在基线时达到或居于第5个百分位数分布的受访者的平均变化,结果。认知能力下降与包括年龄在内的社会人口统计变量显著相关。教育。此外,婚姻状况和家庭构成。报告视力受损的受访者。在控制了多个潜在的混杂因素后,中风和糖尿病的认知功能下降的风险增加。尽管年龄和教育被报道为认知恶化的更显著的预测因素,但其他社会人口和几种医疗状况,包括中风和糖尿病,应该被考虑作为墨西哥裔美国老年人认知老化研究的一部分。
Background. The purpose of this analysis was to examine the association of sociodemographic variables and health-related conditions with 5-year declines in cognitive function function among Mexican American elderly persons.Methods. The cognitive function of 1759 participants was assessed by using the Mini-Mental State Examination (MMSE) in 1993/1994 and again in 1998/1999. Cognitive decline was defined by two sets of criteria: (1) a drop to 17 or below oil the MMSE at follow-up, and (2) a decline of at least three points. the mean change in MMSE scores among respondents who obtained scores at or abode the 5th percentile distribution at baseline,Results. Cognitive decline was significantly associated with sociodemographic variables including, age. education. marital status, and household composition, In addition. respondents with reported vision impairment. stroke, and diabetes were at increased risk for cognitive decline after controlling for multiple potential confounders.Conclusion. Although age and education hake been reported as the more salient predictors of cognitive deterioration, other sociodemographic and several medical condition, including stroke and diabetes should be considered as part of cognitive aging studies among Mexican American elders.