Potential utilities of mask-wearing and instant hand hygiene for fighting SARS-CoV-2
Potential utilities of mask-wearing and instant hand hygiene for fighting SARS-CoV-2
复制标题
DOI：
10.1002/jmv.25805
复制
发表时间：
2020-04-08
影响因子：
12.7
通讯作者：
Chen, Ji-Ming
中科院分区：
文献类型：
--
作者：
Ma, Qing-Xia;Shan, Hu;Chen, Ji-Ming
新型冠状病毒SARS-CoV-2引起的COVID-19大流行的患者激增可能会使许多国家的医疗系统不堪重负。戴口罩和洗手可以减缓病毒的传播，但目前许多国家口罩短缺，及时洗手往往是不可能的。在这项研究中，使用禽流感病毒模拟冠状病毒，评估了三种口罩和即时洗手的效果。使用实时逆转录-聚合酶链反应进行病毒定量。回顾了以往关于戴口罩的研究。结果表明，用含1.00%肥皂粉、0.05%有效氯和0.25%次氯酸钠有效氯的湿毛巾即时擦手，病毒去除率分别为98.36%、96.62%和99.98%。N95口罩、医用口罩、四层厨纸一层布自制口罩，可以阻隔气溶胶中99.98%、97.14%、95.15%的病毒。许多研究支持佩戴医用口罩，但其他研究可能由于错误判断而反对。有了这些数据，我们提出了戴口罩加即时手部卫生（MIH）的方法来减缓病毒的指数传播。MIH的方法得到了七个国家抗击COVID-19的经验的支持。总的来说，一个简单的方法来减缓指数传播的SARS-CoV-2提出了实验，文献综述和控制经验的支持。
The surge of patients in the pandemic of COVID-19 caused by the novel coronavirus SARS-CoV-2 may overwhelm the medical systems of many countries. Mask-wearing and handwashing can slow the spread of the virus, but currently, masks are in shortage in many countries, and timely handwashing is often impossible. In this study, the efficacy of three types of masks and instant hand wiping was evaluated using the avian influenza virus to mock the coronavirus. Virus quantification was performed using real-time reverse transcription-polymerase chain reaction. Previous studies on mask-wearing were reviewed. The results showed that instant hand wiping using a wet towel soaked in water containing 1.00% soap powder, 0.05% active chlorine, or 0.25% active chlorine from sodium hypochlorite removed 98.36%, 96.62%, and 99.98% of the virus from hands, respectively. N95 masks, medical masks, and homemade masks made of four-layer kitchen paper and one-layer cloth could block 99.98%, 97.14%, and 95.15% of the virus in aerosols. Medical mask-wearing which was supported by many studies was opposed by other studies possibly due to erroneous judgment. With these data, we propose the approach of mask-wearing plus instant hand hygiene (MIH) to slow the exponential spread of the virus. This MIH approach has been supported by the experiences of seven countries in fighting against COVID-19. Collectively, a simple approach to slow the exponential spread of SARS-CoV-2 was proposed with the support of experiments, literature review, and control experiences.