Paeonidanins F-H: Three new dimeric monoterpene glycosides from Paeonia lactiflora and their anti-inflammatory activity
Paeonidanins F-H: Three new dimeric monoterpene glycosides from Paeonia lactiflora and their anti-inflammatory activity
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DOI：
10.1016/j.phytol.2015.08.003
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发表时间：
2015-09-01
影响因子：
1.7
通讯作者：
Zou, Liang
中科院分区：
文献类型：
--
作者：
Fu, Qiang;Yu, Tian;Zou, Liang
从中药芍药根中分得三个新的二聚体单萜苷类化合物，即芍药苷F-H（1-3）。根据光谱学证据和水解产物鉴定了它们的结构。化合物1-3显示出对LPS诱导的RAW 246.7巨噬细胞中的一氧化氮（NO）和促炎细胞因子TNF-α释放的抑制作用。(c)2015年欧洲植物化学学会。Elsevier B. V.出版，保留所有权利。
Three new dimeric monoterpene glycosides, paeonidanins F-H (1-3) were isolated from the roots of Paeonia lactiflora. Their structures were elucidated on the basis of spectroscopic evidence and hydrolysis products. Compounds 1-3 showed inhibitory effects against nitric oxide (NO) and pro-inflammatory cytokine TNF-alpha release in LPS-induced RAW 246.7 macrophages. (c) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.