The benefit sharing vision of H3Africa
The benefit sharing vision of H3Africa
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DOI：
10.1111/dewb.12185
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发表时间：
2018-06-01
影响因子：
2.2
通讯作者：
Joffe, Steven
中科院分区：
文献类型：
--
作者：
Dauda, Bege;Joffe, Steven
发展中国家研究的核心伦理原则之一是赞助者有义务使东道国参与者和社区受益。两种已知的利益提供模式主导着发展中国家研究的伦理话语。第一种模式被称为合理可得性，支持在研究结束时提供被证明有效的干预措施的义务。这与第二种模式形成对比，即公平惠益，后者认可东道社区可能认为公平的其他形式的惠益，而不是直接从研究结果中得出的惠益。本文探讨了与非洲人类遗传与健康（H3Africa）研究计划的著作相一致的第三种受益模式。由美国国立卫生研究院、维康信托基金会和非洲人类遗传学会提出的H3Africaa南北合作倡议坚持一种利益模式，即支持将能力建设作为其研究议程的首要义务。这一点从批准加强研究项目能力建设的机制中可以看出。虽然能力建设仍然是提高非洲研究的专门知识、质量和独立性的一个可行手段，但需要采取可持续的措施，以充分发挥非洲主导的非洲大陆研究的潜力。
One of the central ethical tenets of research in developing countries is the sponsor's obligation to benefit host participants and communities. Two known models of benefits provision dominate the ethical discourse of research in developing countries. The first model, known as the reasonable availability, endorses the obligation to provide interventions proven to be effective at the end of a study. This contrasts with the second model, known as fair benefits, which endorses other forms of benefits that host communities may deem as fair beyond those derived directly from the study's findings. This paper explores a third benefit model consistent with the writings of the Human Hereditary and Health in Africa (H3Africa) research initiative. The H3Africaa North-South collaborative initiative predicated by U.S. National Institutes of Health, the Wellcome Trust and the African Society of Human Genetics upholds a benefit model that endorses capacity building as the primary obligation of its research agenda. This is evident by the endorsement of mechanisms to strengthen capacity building in its research projects. While capacity building remains a plausible means of improving the expertise, quality and independence of research in Africa, sustainable measures are needed to realizing the full potential for African-led research on the continent.