ELEVATION OF PLASMA-RENIN ACTIVITY DURING AVOIDANCE PERFORMANCE IN BABOONS
ELEVATION OF PLASMA-RENIN ACTIVITY DURING AVOIDANCE PERFORMANCE IN BABOONS
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DOI：
10.1152/ajplegacy.1976.231.3.772
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发表时间：
1976-01-01
影响因子：
--
通讯作者：
SMITH, OA
中科院分区：
文献类型：
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作者：
BLAIR, ML;FEIGL, EO;SMITH, OA
在狒狒（Papio cynocephalus）中研究了3 h Sidman回避操作性条件反射时间表（按杠杆以避免电击）对血浆肾素活性和肾素底物浓度的影响。在对照日和试验日均采集24 h的血浆样本，并在试验日早晨进行回避试验。血浆肾素活性显着高于试验日在相应的时间的对照日在1，2和3小时后开始的回避试验和30分钟后终止（P = 0.032）。血浆肾素活性增加的幅度与杠杆按压率或电击次数无关。在回避期间或之后，肾素底物浓度没有改变。这些数据表明，血浆肾素活性可以增加心理刺激。
The effect of a 3 h Sidman avoidance operant conditioning schedule (lever pressing to avoid an electric shock) on plasma renin activity and renin substrate concentration was examined in baboons (Papio cynocephalus). Plasma samples were drawn over a 24 h period on both the control and test days, and the avoidance session was presented on the morning of the test day. Plasma renin activity was significantly higher on the test day than at the corresponding hours of the control day at 1, 2 and 3 h after onset of the avoidance test and 30 min after its termination (P = .032). The magnitude of the increase in plasma renin activity was not correlated with either the rate of lever pressing or the number of shocks received. Renin substrate concentration was not changed during or after the avoidance session. These data demonstrate that plasma renin activity can be increased by a psychological stimulus.