The acute retinal necrosis syndrome. Possible herpes simplex retinitis.
The acute retinal necrosis syndrome. Possible herpes simplex retinitis.
复制标题
急性视网膜坏死综合征。
DOI：
10.1016/s0161-6420(84)34109-4
复制
发表时间：
1984
期刊：
影响因子：
13.7
通讯作者：
Z. Zakov
中科院分区：
文献类型：
--
作者：
I. H. Ludwig;H. Zegarra;Z. Zakov
急性视网膜坏死(ARN)综合征是一种伴有血管炎和玻璃体炎的严重坏死性外周视网膜炎。它攻击健康的人，视力预后很差。5例急性肾小球肾炎患者接受治疗。其中两例表现出有趣的临床特征。一名患者出现了双眼ARN综合征，但两次发作间隔了14年，每一次发作之前都有感染性疾病。另一名患者在最初的发病一年后，同一只眼睛可能复发了ARN综合征。每次发作之前，都会出现上呼吸道感染和面部同侧水疱性皮肤损害。一例病变活检在培养中发现单纯疱疹病毒(HSV)。这些联系，虽然不是决定性的，但确实支持了HSV可能是ARN综合征的原因的假设。
The acute retinal necrosis (ARN) syndrome is a severe necrotic peripheral retinitis with vasculitis and vitritis. It attacks healthy people and carries a poor visual prognosis. Five patients with ARN were seen. Two showed interesting clinical features. One patient developed the ARN syndrome in both eyes but with a 14-year hiatus separating the two episodes, each being preceded by an infectious illness. A second patient had a possible recurrence of the ARN syndrome in the same eye, one year after the original episode. Each episode was preceded by an upper respiratory infection and ipsilateral vesicular skin lesions on the face. Biopsy of one lesion yielded herpes simplex virus (HSV) in culture. These associations, although not definitive, do lend support to the hypothesis that HSV may be the cause of the ARN syndrome.