Proteomic Analysis of Azole Resistance in Candida albicans Clinical Isolates

Proteomic Analysis of Azole Resistance in Candida albicans Clinical Isolates
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DOI:
10.1128/aac.48.7.2733-2735.2004
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发表时间:
2004-07
影响因子:
4.9
通讯作者:
Massoumeh Z. Hooshdaran;K. Barker;George M. Hilliard;H. Kusch;J. Morschhäuser;P. D. Rogers
Massoumeh Z. Hooshdaran;K. Barker;George M. Hilliard;H. Kusch;J. Morschhäuser;P. D. Rogers
中科院分区:
医学2区
文献类型:
--
作者:
Massoumeh Z. Hooshdaran;K. Barker;George M. Hilliard;H. Kusch;J. Morschhäuser;P. D. Rogers

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ABSTRACT Changes in protein expression within a matched set of Candida albicans isolates representing the acquisition of azole resistance were examined by two-dimensional polyacrylamide gel electrophoresis and peptide mass fingerprinting. Proteins differentially expressed in association with azole resistance included Grp2p, Ifd1p, Ifd4p, Ifd5p, and Erg10p, a protein involved in the ergosterol biosynthesis pathway.