How many child deaths can we prevent this year?

How many child deaths can we prevent this year?
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DOI:
10.1016/s0140-6736(03)13811-1
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发表时间:
2003-07-05
期刊:
影响因子:
168.9
通讯作者:
Morris, SS
Morris, SS
中科院分区:
医学1区
文献类型:
--
作者:
Jones, G;Steketee, RW;Morris, SS

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这是儿童生存系列五篇论文中的第二篇。第一个重点关注可预防原因导致的持续高儿童死亡率(每年超过 1000 万):腹泻、肺炎、麻疹、疟疾、艾滋病毒/艾滋病、营养不良的根本原因以及导致新生儿死亡的一小部分原因。我们审查了在低收入地区高覆盖率下可行的儿童生存干预措施。设置,并将其分类为 1 级(效果证据充分)、2 级(证据有限)或 3 级(证据不足)。我们的结果表明,至少一种 1 级干预措施可用于预防或治疗 5 岁以下儿童的每种主要死因,但出生窒息除外(可采用 2 级干预措施)。其他几种干预措施的证据也有限。然而,大多数干预措施的全球覆盖率低于 50%。如果普遍采用 1 级或 2 级干预措施,则可以预防 63% 的儿童死亡。这些调查结果表明,实现到 2015 年将儿童死亡率降低三分之二的千年发展目标所需的干预措施是可用的,但这些干预措施尚未提供给有需要的母亲和儿童。
This is the second of five papers in the child survival series. The first focused on continuing high rates of child mortality (over 10 million each year) from preventable causes: diarrhoea, pneumonia, measles, malaria, HIV/AIDS, the underlying cause of undernutrition, and a small group of causes leading to neonatal deaths. We review child survival interventions feasible for delivery at high coverage in low-income. settings, and classify these as level 1 (sufficient evidence of effect), level 2 (limited evidence), or level 3 (inadequate evidence). Our results show that at least one level-1 intervention is available for preventing or treating each main cause of death among children younger than 5 years, apart from birth asphyxia, for which a level-2 intervention is available. There is also limited evidence for several other interventions. However, global coverage for most interventions is below 50%. If level 1 or 2 interventions were universally available, 63% of child deaths could be prevented. These findings show that the interventions needed to achieve the millennium development goal of reducing child mortality by two-thirds by 2015 are available, but that they are not being delivered to the mothers and children who need them.