Rates of human papillomavirus vaccination, attitudes about vaccination, and human papillomavirus prevalence in young women
Rates of human papillomavirus vaccination, attitudes about vaccination, and human papillomavirus prevalence in young women
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DOI：
10.1097/aog.0b013e31817051fa
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发表时间：
2008-05-01
影响因子：
7.2
通讯作者：
Zimet, Gregory D.
中科院分区：
文献类型：
--
作者：
Kahn, Jessica A.;Rosenthal, Susan L.;Zimet, Gregory D.
目的：评估人乳头瘤病毒（HPV）疫苗接种率，与意图和对自己能力的信念相关的因素HPV-6、HPV-11、HPV-16、HPV-18疫苗获得许可后第一年内疫苗型HPV的患病率。从三个初级保健诊所招募了13-26岁的有性经验的女性（N=409），完成了问卷调查，并进行了宫颈阴道HPV DNA检测。结果的措施是HPV疫苗接种，在一个人的能力，接受HPV疫苗在未来一年的意图和信念，和疫苗型HPV的流行。通过逻辑回归分析确定与接受HPV疫苗的意愿和信念独立相关的因素。5%的参与者至少接受了一剂HPV疫苗，66%的人打算接受疫苗，65%的人相信他们可以找到时间接种疫苗，54%的人相信他们可以接受所有三次注射，42%的人认为他们有能力接种疫苗。68%的女性是HPV阳性：9%为HPV-6，3%为HPV-11，17%为HPV-16，12%为HPV-18。与意图独立相关的因素包括相信有影响力的人会批准疫苗接种，宫颈癌或生殖器疣的严重程度较高，安全障碍较少，以及怀孕史。与高度相信一个人接受疫苗的能力相关的因素包括HPV的严重程度、性传播疾病史、保险范围和接种疫苗的实际障碍较少。旨在增加接受HPV疫苗的意愿和信念的干预措施，这可能导致更高的疫苗接种率，应该解决个人对疫苗接种的信念以及接种疫苗的系统性障碍。
OBJECTIVE: To estimate rates of human papillomavirus (HPV) vaccination, factors associated with intention and belief in one's ability (self-efficacy) to receive the vaccine, and prevalence of vaccine-type HPV during the first year after an HPV-6, HPV-11, HPV-16, HPV-18 vaccine was licensed.METHODS: Sexually experienced females 13-26 years of age (N=409) were recruited from three primary care clinics, completed a questionnaire, and underwent cervicovaginal HPV DNA testing. Outcome measures were HPV vaccination, intention and belief in one's ability to receive the HPV vaccine in the next year, and prevalence of vaccine-type HPV. Factors independently associated with intention and belief in one's ability to receive the HPV vaccine were determined by logistic regression.RESULTS: Five percent of participants had received at least one HPV vaccine dose, 66% intended to receive the vaccine, 65% were confident they could find the time to get vaccinated, 54% believed that they could receive all three shots, and 42% believed that they could afford vaccination. Sixty-eight percent of women were HPV-positive: 9% for HPV-6, 3% for HPV-11, 17% for HPV-16, and 12% for HPV-18. Factors independently associated with intention included believing that influential people would approve of vaccination, higher perceived severity of cervical cancer or genital warts, fewer safety barriers, and pregnancy history. Factors associated with a high belief in one's ability to receive the vaccine included perceived severity of HPV, sexually transmitted disease history, insurance coverage, and fewer practical barriers to vaccination.CONCLUSION: Interventions that aim to increase intention and belief in one's ability to receive HPV vaccines, which may lead to higher vaccination rates, should address personal beliefs about vaccination as well as systemic barriers to vaccination.