Stroke admission and case-fatality in an urban medical unit in sub-Saharan Africa: A fourteen year trend study from 1999 to 2012

Stroke admission and case-fatality in an urban medical unit in sub-Saharan Africa: A fourteen year trend study from 1999 to 2012
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DOI:
10.1016/j.jns.2015.02.002
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发表时间:
2015-03-15
影响因子:
4.4
通讯作者:
Kengne, Andre Pascal
Kengne, Andre Pascal
中科院分区:
医学3区
文献类型:
--
作者:
Lekoubou, Alain;Nkoke, Clovis;Kengne, Andre Pascal

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Background: Data on recent stroke trends in the context of rapidly deteriorating risk profile of populations within Africa is very limited. We investigated the admission trend for stroke and related outcomes in a major referral hospital in Cameroon.Methods: Admission and discharge registries, and patient files for the period 1999-2012 of the medical department of the Yaounde Central Hospital were reviewed for evidence of admission for stroke, and outcomes during hospitalization. Trajectories of case-fatality and risk factors over time were assessed, with adjustment for con-founders using logistic regression models.Results: Of the 28,239 medical admissions registered during the study period, 1688 (6.0%) were due to stroke. This proportion ranged from 2.5% in 1999-2000 to 13.1% in 2011-2012 overall and similarly in men and women. Mean age, alcohol consumption and history of stroke varied across years (all p