Re: "incidence of Guillain-Barré syndrome following infection with Campylobacter jejuni".
Re: "incidence of Guillain-Barré syndrome following infection with Campylobacter jejuni".
复制标题
回复：“空肠弯曲菌感染后吉兰-巴利综合征的发生率”。
DOI：
10.1093/aje/154.6.590
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发表时间：
2001
影响因子：
5
通讯作者：
E. Weinberg
中科院分区：
文献类型：
--
作者：
E. Weinberg
McCarthy和Giesecke(1)对由空肠弯曲杆菌引起的格林-巴罗综合征（GBS）进行了对照良好的研究，他们检查了瑞典的29,567名实验室确诊的空肠弯曲杆菌感染患者。作者指出，在6293名20岁以下的人中，没有发现GBS病例。在20,856名20-59岁的成年人中，GBS的发病率为14 / 10万，而在2,417名59岁以上的人群中，发病率为248 / 10万(1)。除了年龄之外，可能导致肠梭菌感染并发症发生GBS的宿主因素还有性别。在英国一组27名空肠梭菌诱导的GBS患者中，男女比例为3.5:1，而在76名没有空肠梭菌感染的GBS患者中，这一比例为1.5:1(2)。
In their well-controlled study of Campylobacter jejuni-induced Guillain-Barré syndrome (GBS), McCarthy and Giesecke (1) examined a Swedish cohort of 29,567 individuals with laboratory-confirmed C. jejuni infection. The authors noted that of 6,293 persons below age 20 years, no cases of GBS were found. Among 20,856 adults aged 20–59 years, the rate of GBS was 14 per 100,000, while in the set of 2,417 people over age 59 years, the rate was 248 per 100,000 (1).A host factor in addition to age that might contribute to the risk of developing GBS as a complication of C. jejuni infection is gender. In a British group of 27 persons with C. jejuni-induced GBS, the ratio of men to women was 3.5: l, whereas in 76 GBS patients with no evidence of C. jejuni infection, the ratio was 1.5: 1 (2).