Aspects of taste and compliance in patients with cancer.
Aspects of taste and compliance in patients with cancer.
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DOI：
10.1016/j.ejon.2005.09.003
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发表时间：
2005-01-01
期刊：
影响因子：
--
通讯作者：
Ravasco, Paula
中科院分区：
文献类型：
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作者：
Ravasco, Paula
味觉改变在癌症患者中很常见，可能是疾病本身和/或其治疗的结果。具体来说，对头部和颈部区域进行化疗和/或放疗已被证明会引起显着的味觉变化。味觉的改变对患者来说是痛苦的，并且可能导致食物厌恶、食物摄入减少和营养缺乏。最终，这可能导致体重减轻，在严重的情况下，营养不良，这与患者预后不良有关，包括对生存的负面影响。为个人量身定制的饮食咨询和建议可以改善营养状况，并且有几种有效的策略可以适应口味变化并增加营养摄入。当饮食摄入不足时，口服补充剂可以提供额外的营养支持。然而，补充剂的成功取决于产品的可接受性和患者的长期依从性。患者的依从性与所感知的补充剂味道有关，这可能受到患者在治疗前后报告的各种味道变化的影响，或者作为疾病进展的结果。提供各种口味的补充剂可能会通过帮助防止味觉疲劳而证明是有益的。此外，个体似乎在治疗期间的不同时间点表现出对特定风味的不同偏好。
Taste alterations are common in patients with cancer, and can be the result of the disease itself and/or its treatment(s). Specifically, chemotherapy and/or radiotherapy to the head and neck area have been shown to induce significant taste changes. Alterations in taste are distressing for patients and can lead to food aversions, a reduction in food intake and nutritional deficits. Ultimately, this can lead to weight loss and, in severe cases, malnutrition, which has been associated with poor patient outcomes, including a negative effect on survival. Dietary counselling and advice tailored to the individual can improve nutritional status, and several effective strategies are available to accommodate taste changes and increase nutritional intake. Oral supplements may provide additional nutritional support when dietary intake is insufficient. The success of supplementation depends, however, on the product acceptability and on patient compliance over the long term. Patient compliance is linked to perceived supplement taste, which may be affected by a variety of taste changes reported by patients both before and after therapy, or as a consequence of disease progression. Supplements which offer a variety of flavours are likely to prove beneficial by helping to prevent taste fatigue. In addition, individuals appear to exhibit distinct preferences for particular flavours at different time points during treatment.