Implementation outcomes of HIV self-testing in low- and middle- income countries: A scoping review.
Implementation outcomes of HIV self-testing in low- and middle- income countries: A scoping review.
复制标题
DOI：
10.1371/journal.pone.0250434
复制
发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Hirschhorn LR
中科院分区：
文献类型：
--
作者：
Rivera AS;Hernandez R;Mag-Usara R;Sy KN;Ulitin AR;O'Dwyer LC;McHugh MC;Jordan N;Hirschhorn LR
HIV自我检测(HIV-ST)是提高HIV检测率的有效手段。低收入和中等收入国家正在采取措施，将艾滋病毒-ST纳入其国家艾滋病毒/艾滋病方案，但很少有审查侧重于在低收入和中等收入国家的执行情况。我们进行了范围审查，以描述和综合现有文献关于HIV-ST在LMIC中的实施结果。我们对Medline、Embase、Global Health、Web of Science和Scopus进行了系统的搜索，并在HIVST.org和其他灰色文献数据库中进行了搜索(完成于2020年9月23日)，并纳入了报告以下八个实施结果中的至少一个的文章：可接受性、适当性、采用率、可行性、保真度、成本、渗透率或可持续性。定量和定性的结果都是以叙事的方式提取和综合的。在这206篇文章中，大多数(75%)收录了侧重于非洲执行情况的文章。艾滋病毒-ST被认为是可接受和适当的，被认为是方便的，并且比标准检测在保密方面更好。然而，缺乏咨询和与护理的联系令利益攸关方感到关切。同行和在线分发被发现在促进采用方面是有效的。用户错误的高发生率是研究报告的一个常见的可行性问题，尽管诊断准确率仍然很高。HIV-ST与较高的计划成本有关，但如果试剂盒价格保持低，且艾滋病毒检测有所改善，则仍可具有成本效益。实施保真度并不总是被报道，关于渗透率和可持续性的研究也很少。证据支持艾滋病毒-ST在LMIC背景下的可接受性、适当性和可行性。成本和用户错误率是成功实施的威胁。未来的研究应该通过衡量渗透率和可持续发展的潜在障碍来解决公平问题，包括分销、成本、扩大规模和安全。
HIV self-testing (HIV-ST) is an effective means of improving HIV testing rates. Low- and middle-income countries (LMIC) are taking steps to include HIV-ST into their national HIV/AIDS programs but very few reviews have focused on implementation in LMIC. We performed a scoping review to describe and synthesize existing literature on implementation outcomes of HIV-ST in LMIC. We conducted a systematic search of Medline, Embase, Global Health, Web of Science, and Scopus, supplemented by searches in HIVST.org and other grey literature databases (done 23 September 2020) and included articles if they reported at least one of the following eight implementation outcomes: acceptability, appropriateness, adoption, feasibility, fidelity, cost, penetration, or sustainability. Both quantitative and qualitative results were extracted and synthesized in a narrative manner. Most (75%) of the 206 included articles focused on implementation in Africa. HIV-ST was found to be acceptable and appropriate, perceived to be convenient and better at maintaining confidentiality than standard testing. The lack of counselling and linkage to care, however, was concerning to stakeholders. Peer and online distribution were found to be effective in improving adoption. The high occurrence of user errors was a common feasibility issue reported by studies, although, diagnostic accuracy remained high. HIV-ST was associated with higher program costs but can still be cost-effective if kit prices remain low and HIV detection improves. Implementation fidelity was not always reported and there were very few studies on, penetration, and sustainability. Evidence supports the acceptability, appropriateness, and feasibility of HIV-ST in the LMIC context. Costs and user error rates are threats to successful implementation. Future research should address equity through measuring penetration and potential barriers to sustainability including distribution, cost, scale-up, and safety.
登录
查看更多内容
DOI：
10.1080/09540121.2018.1537466
发表时间：
2019-02-01
影响因子：
1.7
作者：
Conserve, Donaldson F.;Bay, Camden;Maman, Suzanne
通讯作者：
Maman, Suzanne
影响因子：
6
作者：
Cambiano, Valentina;Johnson, Cheryl C.;Phillips, Andrew
通讯作者：
Phillips, Andrew
DOI：
10.1093/infdis/jiv040
发表时间：
2015-08-15
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
Cambiano V;Ford D;Mabugu T;Napierala Mavedzenge S;Miners A;Mugurungi O;Nakagawa F;Revill P;Phillips A
通讯作者：
Phillips A
DOI：
10.1177/1557988318777674
发表时间：
2018-09
期刊：
American journal of men's health
影响因子：
--
作者：
Conserve DF;Alemu D;Yamanis T;Maman S;Kajula L
通讯作者：
Kajula L
影响因子：
6
作者：
Amstutz, Alain;Kopo, Mathebe;Labhardt, Niklaus D.
通讯作者：
Labhardt, Niklaus D.