RACIAL ETHNIC-DIFFERENCES IN HIV-1 SEROPREVALENCE AND RISKY BEHAVIORS AMONG INTRAVENOUS-DRUG-USERS IN A MULTISITE STUDY
RACIAL ETHNIC-DIFFERENCES IN HIV-1 SEROPREVALENCE AND RISKY BEHAVIORS AMONG INTRAVENOUS-DRUG-USERS IN A MULTISITE STUDY
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DOI：
10.1093/oxfordjournals.aje.a115726
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发表时间：
1990-11-01
影响因子：
5
通讯作者：
SULLIVAN, JL
中科院分区：
文献类型：
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作者：
KOBLIN, BA;MCCUSKER, J;SULLIVAN, JL
在美国马萨诸塞州伍斯特的多个地点招募了西班牙裔、黑人和白人静脉注射吸毒者，研究了人类免疫缺陷病毒1型（HIV-1）血清阳性率、吸毒模式和性行为模式的差异。共采访静脉吸毒人员1092人（男786人，女306人），检出HIV-1抗体874人（80.0%）。在对人口统计学差异进行调整后，与白人男性相比，黑人男性报告危险吸毒行为（曾经共用针头和最近去过射猎场）的可能性要低得多。相比之下，西班牙裔男性更有可能报告最近的危险药物使用行为（在纽约市[美国纽约]共用针头，每天共用针头，参观射击场）。与白人相比，这两个群体都不太可能报告危险的性行为。与白人相比，西班牙裔HIV-1血清阳性的比值比仍然显著大于1（比值比= 4.5），在调整了危险行为和人口统计学变量后，黑人与白人相比，HIV-1血清阳性的比值比保持了边际显著性（比值比= 2.1）。不同种族/族裔吸毒和性行为的不同模式表明需要针对特定人群采取干预措施。
Differences in human immunodeficiency virus type 1 (HIV-1) seroprevalence and patterns of drug-use and sexual behaviors were examined among Hispanic, black, and white intravenous drug users recruited at multiple sites in Worcester, Massachusetts [USA]. A total of 1,092 (786 males, 306 females) intravenous drug users were interviewed, and HIV-1 antibody test results were available for 874 (80.0%). After adjustment for demographic differences, black males were significantly less likely to report risky drug-use behaviors (ever sharing needles and recently visiting shooting galleries) compared with white males. In contrast, Hispanic males were significantly more likely to report recent risky drug-use behaviors (sharing needles in New York City [New York, USA], daily needle-sharing, and visiting shooting galleries). Both groups were less likely to report risky sexual behaviors compared with whites. The odds ratios for HIV-1 seropositivity remained significantly greater than 1 for Hispanics compared with whites (odds ratio = 4.5) and maintained marginal significance for blacks compared with whites (odds ratio = 2.1) when adjusted for risky behaviors and demographic variables. The different patterns of drug-use and sexual behaviors by race/ethnicity indicate the need for interventions targeted to specific populations.