Malabsorption and gastric hyperacidity in systemic mastocytosis. Results of cimetidine therapy.
Malabsorption and gastric hyperacidity in systemic mastocytosis. Results of cimetidine therapy.
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系统性肥大细胞增多症中的吸收不良和胃酸过多。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
Blessing Ld
中科院分区：
文献类型：
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作者：
Bredfeldt Je;O'Laughlin Jc;Durham Jb;Blessing Ld
内脏肥大细胞浸润（系统性肥大细胞增多症）是皮肤肥大细胞增多症的一种罕见表现。症状性胃肠道疾病发生在约四分之一的患者有系统性肥大细胞增多症。一种不常见的胃肠道并发症是吸收不良，在零星的病例报告中有描述。病人胃酸分泌过多和吸收不良的描述。使用组胺H2拮抗剂西咪替丁治疗，改善了患者的胃肠道症状;然而，吸收不良未消退。
Visceral infiltration by mast cells (systemic mastocytosis) is an unusual manifestation of cutaneous mastocytosis. Symptomatic gastrointestinal disease occurs in approximately one-fourth of patients having systemic mastocytosis. An unusual gastrointestinal complication is malabsorption, described in sporadic case reports. A patient with gastric acid hypersecretion and malabsorption is described. Treatment using the histamine H2 antagonist, cimetidine, ameliorated the patient's gastrointestinal symptoms; however, the malabsorption was not resolved.