Molecular biology of oral cavity squamous cell carcinoma.

Molecular biology of oral cavity squamous cell carcinoma.
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DOI:
10.1016/j.oraloncology.2019.104552
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发表时间:
2020-03
期刊:
影响因子:
4.8
通讯作者:
Agrawal N
Agrawal N
中科院分区:
医学2区
文献类型:
--
作者:
Hsu PJ;Yan K;Shi H;Izumchenko E;Agrawal N

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Oral cavity squamous cell carcinoma (OCSCC) is a heterogeneous and complex disease that arises due to dysfunction of multiple molecular signaling pathways. Recent advances in high-throughput genetic sequencing technologies coupled with innovative analytical techniques have begun to characterize the molecular determinants driving OCSCC. An understanding of the key molecular signaling networks underlying the initiation and progression of is essential for informing treatment of the disease. In this chapter, we discuss recent findings of key genes altered in OCSCC and potential treatments targeting these genes.
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