Autism and autism spectrum disorders: diagnostic issues for the coming decade
Autism and autism spectrum disorders: diagnostic issues for the coming decade
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DOI：
10.1111/j.1469-7610.2008.02010.x
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发表时间：
2009-01-01
影响因子：
7.6
通讯作者：
Klin, Ami
中科院分区：
文献类型：
--
作者：
Volkmar, Fred R.;State, Matthew;Klin, Ami
DSM-IV和ICD-10问世至今已有15年。在此期间，这两个诊断系统对自闭症和相关疾病的趋同定义激发了大量的研究。在这篇简短的综述中，我们总结了进展和持续争议的领域，包括自闭症谱系中认知能力更强的个体的诊断方法，非常年幼的婴儿的诊断，亚型的问题以及遗传研究的潜在贡献。使用维度评估具有一些优势，前瞻性研究的见解也是如此。此时，重要的是不仅要研究致病因素，还要研究这些疾病中中断的发育过程。
A decade and a half have elapsed since DSM-IV and ICD-10 appeared. During this time the convergent definitions of autism and related disorders in these two diagnostic systems have stimulated tremendous research. In this brief review we summarize areas of progress and continuing controversy, including approaches to diagnosis in more cognitively able individuals on the autism spectrum, diagnosis in very young infants, the issue of subtypes, and the potential contribution of genetic research. The use of dimensional assessments has some advantages as do the insights from prospective studies. At this point it will be important to study not only causative factors but developmental processes disrupted in these disorders.