Domain specific attentional impairments in children with chromosome 22q11.2 deletion syndrome
Domain specific attentional impairments in children with chromosome 22q11.2 deletion syndrome
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DOI：
10.1016/j.bandc.2007.03.007
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发表时间：
2007-08-01
影响因子：
2.5
通讯作者：
Simon, Tony J.
中科院分区：
文献类型：
--
作者：
Bish, Joel P.;Chiodo, Renee;Simon, Tony J.
染色体22 q缺失综合征（DS22q11.2）的定义认知特征之一是视觉空间处理障碍。本研究的目的是调查和扩展的具体注意的轮廓，这一障碍儿童使用基于对象的注意任务和返回抑制任务。一组患有这种疾病的儿童在这些任务中与一组年龄匹配的典型发育儿童进行了比较。DS22q11.2的儿童表现出受损的空间为基础的定向，这是与以前的研究结果在这组一致。令人惊讶的是，相对于典型的发展组，DS22q11.2的儿童也表现出使用基于对象的线索的能力有所提高。最后，DS22q11.2的儿童表现出完整的返回抑制系统，但是，它似乎是发育延迟。(C)2007爱思唯尔公司All rights reserved.
One of the defining cognitive characteristics of the chromosome 22q deletion syndrome (DS22q11.2) is visuospatial processing impairments. The purpose of this study was to investigate and extend the specific attentional profile of children with this disorder using both an object-based attention task and an inhibition of return task. A group of children with the disorder was compared in these tasks with a group of age-matched typically developing children. The children with DS22q11.2 demonstrated impaired spatially based orienting which is consistent with previous findings in this group. Strikingly, the children with DS22q11.2 also demonstrated an improved ability to use object-based cues, relative to the typically developing group. Finally, the children with DS22q11.2 demonstrated an intact inhibition of return system, however, it appears to be delayed developmentally. (C) 2007 Elsevier Inc. All rights reserved.