Pressure-flow studies in man. An evaluation of the duration of the phases of systole.
Pressure-flow studies in man. An evaluation of the duration of the phases of systole.
复制标题
人体压力流研究。
DOI：
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发表时间：
1969
影响因子：
15.9
通讯作者：
J. Greenfield
中科院分区：
文献类型：
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作者：
A. Harley;C. Starmer;J. Greenfield
本研究旨在评估每搏输出量和心率对收缩期和其他选定血流动力学参数的独立影响。本文用压力梯度技术记录了5例完全性心脏传导阻滞和4例心室起搏引起的房室分离患者在固定心室率下升主动脉的瞬时血压和流量。由于心房收缩对心室充盈的贡献不同，因此在每种心率下观察到的每搏输出量范围很广。结果表明，射血持续时间与每搏输出量有密切的直接线性关系，而心率与每搏输出量的相关性较弱，但两者之间无明显相关性。另一方面，总收缩期的持续时间主要与心率有关，但每搏输出量发挥重要的独立影响。在给定的患者中，射血持续时间和脉压都反映了每搏输出量的变化，并且射血持续时间和脉压的乘积显示出与每搏输出量的良好相关性。
This study was designed to assess the independent effects of stroke volume and heart rate on the phases of systole and other selected hemodynamic parameters. By means of the pressure gradient technique instantaneous blood pressure and flow were recorded in the ascending aorta at fixed ventricular rates in five patients with complete heart block and in four patients with atrio-ventricular dissociation induced by ventricular pacing. Because of the variable contribution of atrial systole to ventricular filling, a wide range of stroke volumes were observed at each heart rate. The results indicate that the duration of ejection bears a close direct linear relationship to stroke volume while heart rate has only a weak but independent relation. On the other hand, the duration of total systole is related chiefly to the heart rate but stroke volume exerts an important independent effect. In a given patient, both duration of ejection and pulse pressure reflect changes of stroke volume and the product of the duration of ejection and the pulse pressure shows a good correlation with the stroke volume.