Primary Malignant Neoplasms of the Duodenum. Excluding the Papilla of Vater
Primary Malignant Neoplasms of the Duodenum. Excluding the Papilla of Vater
复制标题
原发性十二指肠恶性肿瘤。
DOI：
10.1016/s0016-5085(56)80106-6
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发表时间：
1956
期刊：
影响因子：
--
通讯作者：
J. Cain
中科院分区：
文献类型：
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作者：
A. Burgerman;A. Baggenstoss;J. Cain
除 Vater 乳头外，十二指肠原发性恶性肿瘤很少见。 1910 年至 1953 年间，梅奥诊所尸检时发现了 31 例病例，发病率为 0.12%。 31 个肿瘤中有 27 个是腺癌；其余4个是各种类型的肉瘤。该系列中没有证据表明良性溃疡发生了肿瘤性改变。 31例中有20例发生转移。最常见的转移部位是区域淋巴结和肝脏。该系列中最常见的临床特征是疼痛、体重减轻、呕吐和贫血。黑便、黄疸和腹部肿块也是突出的发现。 22例中15例经X线检查发现病变。在没有病变的阳性 X 线学证据的情况下，任何情况下都无法做出正确的诊断。
Primary malignant neoplasms of the duodenum, excluding the papilla of Vater, are rare. Thirty-one cases were found at necropsy at the Mayo Clinic from 1910 through 1953, an incidence of 0.12 per cent. Twenty-seven of the 31 tumors were adenocarcinomas; the remaining 4 were sarcomas of various types. There was no evidence in this series that a benign ulcer had undergone neoplastic change. Metastasis had occurred in 20 of the 31 cases. The commonest sites of metastasis were the regional lymph nodes and the liver.The commonest clinical features in this series were pain, loss of weight, vomiting and anemia. Melena, jaundice and an abdominal mass were also prominent findings. A lesion was found by roentgenologic examination in 15 of 22 cases. In no case was a correct diagnosis made without positive roentgenologic evidence of the lesion.