Human minisatellite mutation rate after the Chernobyl accident
Human minisatellite mutation rate after the Chernobyl accident
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DOI：
10.1038/380683a0
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发表时间：
1996-04-25
期刊：
影响因子：
64.8
通讯作者：
Jeffreys, AJ
中科院分区：
文献类型：
--
作者：
Dubrova, YE;Nesterov, VN;Jeffreys, AJ
在切尔诺贝利事故后白俄罗斯莫吉廖夫区重污染地区的儿童角和对照人群中研究了人类小卫星基因座的生殖系突变。突变的频率被认为是两倍高，在对照组的家庭接触。Mogilev家族的突变率与铯-137表面污染水平相关，与生殖系突变的辐射诱导一致。
Germline mutation at human minisatellite loci has been studied among children horn in heavily polluted areas of the Mogilev district of Belarus after the Chernobyl accident and in a control population. The frequency of mutation was found to be twice as high in the exposed families as in the control group. Mutation rate in the Mogilev families was correlated with the level of caesium-137 surface contamination, consistent with radiation induction of germline mutation.