Experts do not agree when to treat retinopathy of prematurity based on plus disease
Experts do not agree when to treat retinopathy of prematurity based on plus disease
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DOI：
10.1136/bjophthalmol-2011-300573
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发表时间：
2012-04-01
影响因子：
4.1
通讯作者：
La Cour, Morten
中科院分区：
文献类型：
--
作者：
Slidsborg, Carina;Forman, Julie Lyng;La Cour, Morten
目的调查五个严重程度的中央血管变化（无，轻度，中度，重度前加疾病，加疾病）和侵略性后部视网膜病变的早产儿（ROP）的阅片人之间的协议，并看看是否意外的转变，在适应症治疗happened.Methods四个国际ROP读者参加。在对照片进行分级之前，读者被告知包括了高比例的晚期ROP病例。总共有243张照片/948个象限，来自136名婴儿。作为一个标准的一系列的照片，分级进行优化conditions.Results的四个读者同意的象限分数只有70（7.38%）的948象限，也就是说，在1，5，15，4和45象限分数0，1，2，3和4，分别。阅读者之间的平均得分存在系统性差异（排列检验，p
Objectives To investigate inter-reader agreement on five severity levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.Methods Four international ROP readers participated. Before the grading of the photographs, the readers were informed that a high proportion of advanced ROP cases were included. In total, 243 photographs/948 quadrants were available from 136 infants. As a standard series of photographs was available, grading was performed under optimised conditions.Results The four readers agreed on the quadrant scores of only 70 (7.38%) of the 948 quadrants-that is, on 1, 5, 15, 4 and 45 quadrants for scores 0, 1, 2, 3 and 4, respectively. The mean scores differed systematically between the readers (permutation test, p