Using GLIM criteria, cutoff value for low BMI in Asian populations discriminates high or low muscle mass: A cross-sectional study
Using GLIM criteria, cutoff value for low BMI in Asian populations discriminates high or low muscle mass: A cross-sectional study
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DOI：
10.1016/j.nut.2020.110928
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发表时间：
2021-01-01
期刊：
影响因子：
4.4
通讯作者：
Moriyama, Hideki
中科院分区：
文献类型：
--
作者：
Akazawa, Naoki;Kishi, Masaki;Moriyama, Hideki
目的：本研究的目的是根据全球营养不良领导倡议 (GLIM) 标准，检查中度和重度低体重指数 (BMI) 患者之间的肌肉质量和肌内脂肪组织是否存在差异，该差异是根据全球营养不良领导倡议 (GLIM) 标准，以亚洲人群 >70 岁患者中低 BMI 的临界值来区分的。方法：这项横断面研究包括 345 名体重为 17.8 kg/m(2) 的住院患者； n = 96)、中度低 BMI (20 kg/m(2)；n = 81) 和正常 BMI (20 kg/m(2)；n = 168)。超声图像通过B型超声成像获得。分别根据肌肉厚度和回声强度评估股四头肌的肌肉质量和肌内脂肪组织。采用协方差分析来检验三组间股四头肌厚度和回声强度的差异。结果：BMI严重低、中低和正常组的股四头肌厚度和回声强度分别为0.9±0.3、1.1±0.4、1.4±0.5cm和93.3±20.8、91.3±19.3、80.1分别为+/- 21.6。重度低BMI组股四头肌厚度显着低于中低BMI组（P < 0.001）和正常BMI组（P < 0.001），中低BMI组股四头肌厚度也显着低于正常BMI组（P < 0.001）。三组之间股四头肌回声强度没有显着差异。结论：低 BMI 的截止值可区分肌肉质量的高低。本研究的结果支持17.8 kg/m(2)作为低BMI的临界值的有效性，根据GLIM标准从肌肉质量的角度对70岁以上亚洲人群营养不良的严重程度进行分级。 (c) 2020 Elsevier Inc. 保留所有权利。
Objectives: The aim of this study was to examine whether differences in muscle mass and intramuscular adipose tissue are present between patients with a moderately and severely low body mass index (BMI) as discriminated by the cutoff value for a low BMI among patients >70 y of age in Asian populations according to the Global Leadership Initiative on Malnutrition (GLIM) criteria.Methods: This cross-sectional study included 345 inpatients 17.8 kg/m(2); n = 96), moderately low BMI ( 20 kg/m(2); n = 81), and normal BMI ( 20 kg/m(2); n = 168). Ultrasound images were obtained with B-mode ultrasound imaging. Muscle mass and intramuscular adipose tissue of the quadriceps were assessed based on the muscle thickness and echo intensity, respectively. Analysis of covariance was used to examine the differences in the quadriceps thickness and echo intensity among the three groups.Results: The quadriceps thickness and echo intensity in the severely low, moderately low, and normal BMI groups were 0.9 0.3, 1.1 +/- 0.4, and 1.4 +/- 0.5 cm and 93.3 +/- 20.8, 91.3 +/- 19.3, 80.1 +/- 21.6, respectively. The quadriceps thickness in the severely low BMI group was statistically significantly lower than that in the moderately low BMI (P < 0.001) and normal BMI (P < 0.001) groups, and the quadriceps thickness in the moderately low BMI group was also statistically significantly lower than that in the normal BMI group (P < 0.001). The quadriceps echo intensity showed no significant differences among the three groups.Conclusions: The cutoff value for a low BMI discriminates high or low muscle mass. Results of this study sup ported the validity of 17.8 kg/m(2) as the cutoff value for a low BMI with which to grade the severity of malnutrition in Asian populations >70 y of age according to the GLIM criteria from the perspective of muscle mass. (c) 2020 Elsevier Inc. All rights reserved.