Iron Nutrition and Anaemia in Piglets: a Review -
Iron Nutrition and Anaemia in Piglets: a Review -
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发表时间：
2012
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通讯作者：
Victor Ishaya
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作者：
Victor Ishaya
人类早就知道铁在健康和疾病中起着重要作用（Loosli, 1978）。Bryan,（1931）指出，有文献记载的铁的治疗用途可以追溯到公元前1500年。铁被认为是动物的重要营养物质（Boussingault, 1872）。Braasch,（1981）是第一个描述在德国月子饲养的哺乳猪贫血的人。然而，他并没有将贫血等同于缺铁，而是将其等同于管理。McGowan和Chrichton（1924）首次将哺乳猪的贫血症与缺铁联系起来。铁是所有生物的重要组成部分。Bothwell等人（1988）估计，一个体重70公斤的成年人体内的铁含量为百万分之60-70。仔猪出生时的浓度为20-30 ppm （Venn et al, 1977）。在仔猪的这种浓度中，475%与血液有关，1.6%在脾脏，15%在肝脏，其余44%在身体组织中发现（Thoren-Tolling, 1995）。在新生儿期之后，大约80%的猪与血红蛋白（Hb）有关{国家研究委员会1979}。大多数体内铁以血红素复合物或非血红素复合物的形式与蛋白质结合。最常见的血红素复合物是血红蛋白和肌红蛋白，而常见的非血红素复合物有两种储存形式，即铁蛋白和血黄素，以及一种运输形式，即转移蛋白。
Abstract Man has known that iron plays an important role in health and disease for considerable time (Loosli, 1978). Bryan, (1931) stated that documented therapeutic use of iron date back as far as 1500BC. Iron was recognised as vital nutrient for animal (Boussingault, 1872). Braasch, (1981) was the first to describe anaemia in nursing pigs that were being reared in confinement in Germany. However, he didn’t equate the anaemia with iron deficiency but instead with management. Anaemia in nursing pigs was first link to iron deficiency by McGowan and Chrichton (1924). Iron is a very vital component of every living thing. Bothwell et al., (1988), estimated that a 70kg adult human has a whole body iron of 60-70 parts per million (ppm). The concentration in piglets at birth is 20-30 ppm (Venn et al 1977). Of this concentration in the piglet, 475 is associated with blood, 1.6% in the spleen, 15% in the liver and th remaining 44% is found in body tissues (Thoren-Tolling, 1995). Following the neonatal period around 80% in the pig is associated with haemoglobin (Hb) {National Research Council 1979}. Th majority of body iron is bound to proteins as heme complexes or nonheme complexes. The most common heme complexes are Hb and myoglobin, while the common nonheme complexes are of two storage forms viz: feritin and haemosiderin, and one transport form called transferin.