Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation
Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation
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DOI：
10.1038/ja.2009.19
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发表时间：
2009-04-01
影响因子：
3.3
通讯作者：
Tomoda, Hiroshi
中科院分区：
文献类型：
--
作者：
Yamazaki, Hiroyuki;Omura, Satoshi;Tomoda, Hiroshi
通过光谱研究，包括各种NMR实验，阐明了青霉菌FKI-3765-1产生的小鼠巨噬细胞中脂滴形成的新抑制剂pentacecilides的结构。戊酰脲具有共同的五环半萜核，其含有芳环和δ-内酯环。The Journal of Antibiotics（2009）62，207-211; doi：10.1038/ja.2009.19; 2009年3月20日在线发表
The structures of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1, were elucidated by spectroscopic studies, including various NMR experiments. Pentacecilides have a common pentacyclic meroterpene core, which contains an aromatic ring and a delta-lactone ring. The Journal of Antibiotics (2009) 62, 207-211; doi:10.1038/ja.2009.19; published online 20 March 2009