The genetics of postzygotic isolation in the Drosophila virilis group.
The genetics of postzygotic isolation in the Drosophila virilis group.
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果蝇 virilis 群体合子后分离的遗传学。
DOI：
10.1093/genetics/121.3.527
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发表时间：
1989
期刊：
影响因子：
3.3
通讯作者：
Coyne,JA
中科院分区：
文献类型：
--
作者：
Orr,HA;Coyne,JA
在一项对果蝇（Drosophila virilis）种群中合子后生殖隔离的遗传学研究中，我们发现X染色体对雄性和雌性杂种不育和不活力的影响最大。单独的X有一个明显的影响密切相关的物种之间的合子后隔离。涉及更远的相关物种的杂交也显示出较大的X效应，尽管常染色体也可能发挥作用。在唯一的杂交尚未进行这样的分析，我们表明，杂种雄性和雌性不育的结果，从不同的X-连锁基因座的作用。我们的研究结果与其他类群的遗传研究结果雅阁，并支持Hallaun的规则（异配子F1不育或不活力）和X染色体对生殖隔离的巨大影响是由自然选择积累的部分隐性或欠显性突变的结果。我们还描述了一种方法，允许遗传分析的物种之间的生殖隔离，产生完全不育或无效的杂交种。这种物种对代表了物种形成的最后阶段，不能用传统方法进行分析。X染色体在这些物种之间的合子后隔离中也起着重要作用。
In a genetic study of postzygotic reproductive isolation among species of the Drosophila virilis group, we find that the X chromosome has the largest effect on male and female hybrid sterility and inviability. The X alone has a discernible effect on postzygotic isolation between closely related species. Hybridizations involving more distantly related species also show large X-effects, although the autosomes may also play a role. In the only hybridization yet subjected to such analysis, we show that hybrid male and female sterility result from the action of different X-linked loci. Our results accord with genetic studies of other taxa, and support the view that both Haldane's rule (heterogametic F1 sterility or inviability) and the large effect of the X chromosome on reproductive isolation result from the accumulation by natural selection of partially recessive or underdominant mutations. We also describe a method that allows genetic analysis of reproductive isolation between species that produce completely sterile or inviable hybrids. Such species pairs, which represent the final stage of speciation, cannot be analyzed by traditional methods. The X chromosome also plays an important role in postzygotic isolation between these species.