Genetic Variation of the Mitochondrial DNA Cytochrome b Region in Japanese Native Dog Breeds (Canis familiaris)
Genetic Variation of the Mitochondrial DNA Cytochrome b Region in Japanese Native Dog Breeds (Canis familiaris)
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日本本土犬种（Canisamilis）线粒体 DNA 细胞色素 b 区的遗传变异
DOI：
10.2108/zsj.15.699
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
M. Sahara
中科院分区：
文献类型：
--
作者：
N. Okumura;N. Ishiguro;M. Nakano;A. Matsui;M. Sahara
本文测定了94条狗（包括73只日本本土动物）线粒体DNA细胞色素B基因（cyt B）的部分序列（454个碱基）。该区域有13个核苷酸位置发生了核苷酸替换，均为转换。13个核苷酸替换中有3个是非同义的。共发现14个cyt B单倍型，但日本本土犬品种不能区分为不同的聚类系统发育树。这些结果支持了以前的观点，即在日本本土犬种中观察到的遗传变异可能是由于杂交和/或近交造成的。
Abstract Partial sequences (454 bases) of the mitochondrial DNA (mtDNA) cytochrome b gene (cyt b) were determined for 94 dogs including 73 Japanese native animals. Thirteen nucleotide positions of this region showed nucleotide substitutions, which were all transitions. Three of 13 nucleotide substitutions were nonsynonymous. A total of 14 cyt b haplotypes were found, but the Japanese native dog breeds could not be differentiated as distinct clusters in phylogenetic trees. These results support the previous view that genetic variations observed among Japanese native dog breeds could have resulted from interbreeding and/or intrabreeding.