A novel monosialoganglioside synthesized by a rat brain cytidine-5'-monophospho-N-acetylneuraminic acid: galactosyl-N-acetylgalactosaminyl-galactosyl-glucosylceramide sialyltransferase.
A novel monosialoganglioside synthesized by a rat brain cytidine-5'-monophospho-N-acetylneuraminic acid: galactosyl-N-acetylgalactosaminyl-galactosyl-glucosylceramide sialyltransferase.
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由大鼠脑胞苷-5-单磷酸-N-乙酰神经氨酸合成的新型单唾液酸神经节苷脂：半乳糖基-N-乙酰半乳糖胺基-半乳糖基-葡萄糖基神经酰胺唾液酸转移酶。
DOI：
10.1016/0006-291x(73)90155-1
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发表时间：
1973
影响因子：
3.1
通讯作者：
M. C. Yip
中科院分区：
文献类型：
--
作者：
M. C. Yip
本文报道了幼年大鼠脑内胞苷-5 ′-单磷酸-N-乙酰神经氨酸：半乳糖基-N-乙酰氨基半乳糖基-葡萄糖神经酰胺唾液酸转移酶。酶解产物是一种新的含有神经氨酸酶不稳定的神经氨酸的单唾液酸神经节苷脂。这种新的单唾液酸神经节苷脂的结构如下：N-乙酰神经氨酰（2→3）半乳糖基（β，1→3）N-乙酰半乳糖胺酰（β，1→4）半乳糖基（β，1→4）葡萄糖基（1→1）神经酰胺。
The present paper reports a cytidine-5′-monophospho-N-acetylneuraminic acid: galactosyl-N-acetylgalactosaminyl-galactosyl-glucosylceramide sialyltransferase in young rat brain. The enzymic product is a new monosialoganglioside containing a neuraminidase-labile neuraminic acid. The proposed structure for this novel monosialoganglioside is as follows: N-acetylneuraminyl(2→3)Galactosyl(β, 1→3)N-acetylgalactosaminyl(β, 1→4)Galactosyl(β, 1→4)Glucoayl(1→1)ceramide.