Diagnostic performance of susceptibility-weighted magnetic resonance imaging for the detection of calcifications: A systematic review and meta-analysis.
Diagnostic performance of susceptibility-weighted magnetic resonance imaging for the detection of calcifications: A systematic review and meta-analysis.
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DOI：
10.1038/s41598-017-15860-1
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发表时间：
2017-11-14
影响因子：
4.6
通讯作者：
Makowski MR
中科院分区：
文献类型：
--
作者：
Adams LC;Bressem K;Böker SM;Bender YY;Nörenberg D;Hamm B;Makowski MR
自推出以来，磁共振成像（SW-MRI）已显示出克服MRI对钙化不敏感的潜力。先前报告SW-MRI和磁共振成像（MRI）检测钙化的诊断性能的研究不一致，并且基于单机构设计。据我们所知，这是第一个关于SW-MRI的荟萃分析，确定了SW-MRI检测钙化的潜力。两名独立研究者检索了MEDLINE、EMBASE和Web of Science，以获得合格的诊断准确性研究，这些研究发表于2017年3月24日，并使用计算机断层扫描（CT）作为参考，研究了SW-MRI检测钙化的准确性。QUADAS-2工具用于评估研究质量，分析方法基于PRISMA。应用双变量诊断随机效应模型获得合并的敏感性和特异性。在通过系统性文献检索检索到的4629项研究中，纳入了12项临床研究（962例患者，共1,032处钙化）。SW-MRI的合并灵敏度为86.5%（95%置信区间（CI）：73.6-93.7%），标准MRI为36.7%（95% CI：29.2-44.8%）。SW-MRI（90.8%; 95%-CI：81.0-95.8%）和标准MRI（94.2; 95%-CI：88.9-96.7%）的合并特异性相当。本荟萃分析的结果表明，SW-MRI是检测软组织钙化的可靠方法。
Since its introduction, susceptibility-weighted-magnetic resonance imaging (SW-MRI) has shown the potential to overcome the insensitivity of MRI to calcification. Previous studies reporting the diagnostic performance of SW-MRI and magnetic resonance imaging (MRI) for the detection of calcifications are inconsistent and based on single-institution designs. To our knowledge, this is the first meta-analysis on SW-MRI, determining the potential of SW-MRI to detect calcifications. Two independent investigators searched MEDLINE, EMBASE and Web of Science for eligible diagnostic accuracy studies, which were published until March 24, 2017 and investigated the accuracy of SW-MRI to detect calcifications, using computed tomography (CT) as a reference. The QUADAS-2 tool was used to assess study quality and methods for analysis were based on PRISMA. A bivariate diagnostic random-effects model was applied to obtain pooled sensitivities and specificities. Out of the 4629 studies retrieved by systematic literature search, 12 clinical studies with 962 patients and a total of 1,032 calcifications were included. Pooled sensitivity was 86.5% (95%-confidence interval (CI): 73.6–93.7%) for SW-MRI and 36.7% (95%–CI:29.2–44.8%) for standard MRI. Pooled specificities of SW-MRI (90.8%; 95%–CI:81.0–95.8%) and standard MRI (94.2; 95%–CI:88.9–96.7%) were comparable. Results of the present meta-analysis suggest, that SW-MRI is a reliable method for detecting calcifications in soft tissues.
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影响因子：
15.8
作者：
Moher D;Liberati A;Tetzlaff J;Altman DG;PRISMA Group
通讯作者：
PRISMA Group
影响因子：
3.7
作者：
Adams, Lisa C.;Boeker, Sarah M.;Makowski, Marcus R.
通讯作者：
Makowski, Marcus R.
影响因子：
7.2
作者：
Deeks, JJ;Macaskill, P;Irwig, L
通讯作者：
Irwig, L
影响因子：
4.7
作者：
Gasparotti, Roberto;Pinelli, Lorenzo;Liserre, Roberto
通讯作者：
Liserre, Roberto
DOI：
10.3174/ajnr.a1461
发表时间：
2009-02
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
Mittal S;Wu Z;Neelavalli J;Haacke EM
通讯作者：
Haacke EM