Theoretical and practical considerations on detection performance of time domain, Fourier domain, and swept source optical coherence tomography
Theoretical and practical considerations on detection performance of time domain, Fourier domain, and swept source optical coherence tomography
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DOI：
10.1117/1.2753410
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发表时间：
2007-07-01
影响因子：
3.5
通讯作者：
Brezinski, Mark E.
中科院分区：
文献类型：
--
作者：
Liu, Bin;Brezinski, Mark E.
基于光谱干涉的光学相干层析成像（OCT）最近已被研究，作者经常建议与时域方法相比具有上级性能。这些技术具有类似的分辨率，并且光谱技术目前可能要求更快的采集速率。与目前的许多观点相反，它们的检测参数可能较差。动态范围和信噪比（SNR）与图像穿透相关，对比度是深度的函数。这项工作研究的理论灵敏度，动态范围，和SNR的技术，在光电子学的实际限制，考虑到经常被忽视或误解的经典因素，影响性能，如低频噪声，模拟到数字（AD）转换损耗，和潜在的提高灵敏度的方法，包括快速激光扫描。这些技术相对于这些参数进行比较。虽然傅立叶域OCT具有一些优点，如信号积分，但对于非透明组织，其缺点似乎不太可能最终被克服。最后，时域（TD）-OCT似乎在SNR和动态范围方面具有上级性能。对于眼睛的透明组织可能不是这种情况。扫频光源OCT的某些积极方面留下了其性能可能接近不透明组织中的（TD）-OCT的性能的可能性。(C)2007年，由光学仪器工程师协会（Society of Photo-Optical Instrumentation Engineers）主办。
Optical coherence tomography (OCT) based on spectral interferometry has recently been examined, with authors often suggesting superior performance compared with time domain approaches. The technologies have similar resolutions and the spectral techniques may currently claim faster acquisition rates. Contrary to many current opinions, their detection parameters may be inferior. The dynamic range and signal-to-noise ratio (SNR) correlate with image penetration, the contrast as a function of depth. This work examines the theoretical sensitivity, dynamic range, and SNR of the techniques, within the practical limits of optoelectronics, taking into account often ignored or misunderstood classical factors that affect performance, such as low frequency noise, analog to digital (AD) conversion losses, and methods for potentially improving sensitivity, including fast laser sweeping. The technologies are compared relative to these parameters. While Fourier domain OCT has some advantages such as signal integration, it appears unlikely that its disadvantages can ultimately be overcome for nontransparent tissue. Ultimately, time-domain (TD)-OCT appears to have the superior performance with respect to SNR and dynamic range. This may not be the case for transparent tissue of the eye. Certain positive aspects of swept source OCT leave the possibility open that its performance may approach that of (TD)-OCT in nontransparent tissue. (C) 2007 Society of Photo-Optical Instrumentation Engineers.