"Core" RxLR effectors in phytopathogenic oomycetes: A promising way to breeding for durable resistance in plants?

"Core" RxLR effectors in phytopathogenic oomycetes: A promising way to breeding for durable resistance in plants?
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DOI:
10.1080/21505594.2021.1948277
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发表时间:
2021-12
期刊:
影响因子:
5.2
通讯作者:
Moleleki LN
Moleleki LN
中科院分区:
生物学2区
文献类型:
--
作者:
Chepsergon J;Motaung TE;Moleleki LN

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Phytopathogenic oomycetes are known to successfully infect their hosts due to their ability to secrete effector proteins. Of interest to many researchers are effectors with the N-terminal RxLR motif (Arginine-any amino acid-Leucine-Arginine). Owing to advances in genome sequencing, we can now comprehend the high level of diversity among oomycete effectors, and similarly, their conservation within and among species referred to here as “core” RxLR effectors (CREs). Currently, there is a considerable number of CREs that have been identified in oomycetes. Functional characterization of these CREs propose their virulence role with the potential of targeting central cellular processes that are conserved across diverse plant species. We reason that effectors that are highly conserved and recognized by the host, could be harnessed in engineering plants for durable as well as broad-spectrum resistance.
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