The role of human parietal cortex in attention networks
The role of human parietal cortex in attention networks
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DOI：
10.1093/brain/awh071
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发表时间：
2004-03-01
期刊：
影响因子：
14.5
通讯作者：
Zhai, RY
中科院分区：
文献类型：
--
作者：
Han, SH;Jiang, Y;Zhai, RY
顶叶皮层被认为是引导空间注意力的神经网络的一部分。然而，目前尚不清楚顶叶皮层在多大程度上参与了视觉皮层活动的注意调节和额叶皮层在注意网络中的参与。我们使用功能性磁共振成像记录了一名局灶性左顶叶损伤患者在隐蔽的视觉定向任务中需要在有人看管或无人看管的位置检测目标的行为表现和血流动力学反应。患者对左视野刺激的反应时间因有效提示而比无效提示加快，而对LVF刺激的注意与右侧纹外皮层、右侧顶叶和扣带皮层以及双侧额叶皮层的活动增强有关。然而，患者对右视野刺激的行为和神经反应不受提示效度的影响。这些结果讨论了人类顶叶皮层在神经网络基础的自愿注意控制的作用。
The parietal cortex has been proposed as part of the neural network for guiding spatial attention. However, it is unclear to what degree the parietal cortex contributes to the attentional modulations of activities of the visual cortex and the engagement of the frontal cortex in the attention network. We recorded behavioural performance and haemodynamic responses using functional MRI from a patient with focal left parietal damage in covert visual orienting tasks requiring detection of targets at the attended or unattended locations. While the patient's reaction times to left visual field stimuli were speeded by valid relative to invalid cues, attention to LVF stimuli was associated with enhanced activities in the right extrastriate cortex, right parietal and cingulate cortices, and bilateral frontal cortices. However, the patient's behavioural and neural responses to right visual field stimuli were not influenced by cue validity. The results are discussed in terms of the role of human parietal cortex in the neural network underlying voluntary attentional control.