Behavioral risk factors and human immunodeficiency virus (HIV) prevalence among intravenous drug users in Puerto Rico.
Behavioral risk factors and human immunodeficiency virus (HIV) prevalence among intravenous drug users in Puerto Rico.
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波多黎各静脉吸毒者的行为危险因素和人类免疫缺陷病毒（HIV）患病率。
DOI：
10.1093/oxfordjournals.aje.a116320
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发表时间：
1992
影响因子：
5
通讯作者：
Reyes,JC
中科院分区：
文献类型：
--
作者：
Robles,RR;Colón,HM;Sahai,H;Matos,TD;Marrero,CA;Reyes,JC
本研究报告的四个经验模型可能有助于了解与人类免疫缺陷病毒（HIV）之间的静脉吸毒者的行为。样本包括1989年5月至1990年6月在波多黎各的圣胡安招募的1，637名静脉注射毒品使用者。调整社会人口统计学，四个逻辑回归模型，以评估与艾滋病毒血清阳性的危险行为的关联。在模型1中，发现与艾滋病毒血清阳性显着相关的变量是每天注射四次，注射是唯一的吸毒途径，以及注射年数。在模型2中，唯一与HIV血清阳性显著相关的危险行为是在射击场注射毒品。在模型3中，所有性别风险变量均未达到调整后的显著性水平。在模型4中，肺炎、肝炎和梅毒与HIV感染显著相关。为了评估四个模型中每个模型中显著变量的个体效应，同时控制所有变量进行逻辑回归分析。校正Bonferroni校正后，年龄组25-34岁，注射作为使用药物的唯一途径，注射年数和梅毒是唯一剩下的显著变量。
This study reports on four empirical models likely to contribute to understanding the behaviors linked with human immunodeficiency virus (HIV) among intravenous drug users. The sample comprises 1,637 intravenous drug users recruited between May 1989 and June 1990 in San Juan, Puerto Rico. Adjusting for sociodemographics, four logistic regression models were constructed to assess the association of risk behaviors with HIV seropositivity. In model 1, the variables found to be significantly associated with HIV seropositivity were injecting four times a day, injection as the only route of consuming drugs, and years of injection. In model 2, the only risk behavior significantly associated with HIV seropositivity was injecting drugs in shooting galleries. In model 3, all sex risk variables failed to meet the adjusted level of significance. In model 4, pneumonia, hepatitis, and syphilis were significantly linked with HIV infection. In order to assess the individual effects of the significant variables in each one of the four models, a logistic regression analysis was performed simultaneously controlling for all of the variables. After adjustment for the Bonferroni correction, age group 25–34 years, injection as the only route of using drugs, number of years of injection, and syphilis were the only significant variables remaining.