Distribution of Group-Specific Component/Vitamin D-Binding Protein Alleles in Southwestern Japan and Geographical Clines of Allele Frequencies in Japanese Populations
Distribution of Group-Specific Component/Vitamin D-Binding Protein Alleles in Southwestern Japan and Geographical Clines of Allele Frequencies in Japanese Populations
复制标题
日本西南部群体特异性成分/维生素 D 结合蛋白等位基因的分布和日本人群等位基因频率的地理谱系
DOI：
10.1537/ase.106.385
复制
发表时间：
1998
影响因子：
0.7
通讯作者：
O. Tsuganezawa
中科院分区：
文献类型：
--
作者：
K. Ago;I. Yuasa;O. Tsuganezawa
为了研究日本群体特异性组分/维生素D结合蛋白（GC）系统等位基因频率的地理倾斜，测定了包括冲绳在内的日本西南部9个群体的GC类型。在岛屿人群中，特别是屋久岛和宫古的常见等位基因的频率被发现比在日本大陆人群中更广泛地分散。GC* 1A 2在除最西南的岛屿宫古和石垣外的所有种群中均表现出多态性。GC*1F、GC* 1 S和GC*2频率的地理倾斜与弥生时代的迁移有关。
To scrutinize the geographical clines of allele frequencies of the group-specific component/vitamin-D binding protein (GC) system in Japan, the GC types in nine populations of southwestern Japan including Okinawa were determined. The frequencies of the common alleles in the island populations, especially, Yakushima and Miyako were found to be scattered more extensively than those in the populations of the mainland Japan. GC*1A2 was polymorphic in all populations except in the southwesternmost islands, Miyako and Ishigaki. The geographical clines of GC*1F, GC*1S and GC*2 frequencies are discussed in connection with the migration of the Yayoi era.