Tandem aldol-allylation and aldol-aldol reactions with ketone-derived enolsilanes: Highly diastereoselective single-step synthesis of complex tertiary carbinols
Tandem aldol-allylation and aldol-aldol reactions with ketone-derived enolsilanes: Highly diastereoselective single-step synthesis of complex tertiary carbinols
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DOI：
10.1021/ja053593s
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发表时间：
2005-09-21
影响因子：
15
通讯作者：
Leighton, JL
中科院分区：
文献类型：
--
作者：
Wang, XL;Meng, QL;Leighton, JL
A new tandem aldol−allylation reaction employing ketone-derived enolates has been developed that leads to the rapid, diastereoselective synthesis of tertiary carbinol containing fragments with relevance to polyketide natural product synthesis. In addition, the use of ketone-derived enolates has led to the development of a new tandem aldol−aldol reaction.
