Neurotransmitter dysfunction in patients with borderline personality disorder
Neurotransmitter dysfunction in patients with borderline personality disorder
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DOI：
10.1016/s0193-953x(05)70141-6
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发表时间：
2000-03-01
影响因子：
1.7
通讯作者：
Siever, LJ
中科院分区：
文献类型：
--
作者：
Gurvits, IG;Koenigsberg, HW;Siever, LJ
神经递质系统功能障碍可能与边缘型人格障碍的冲动性攻击和情感不稳定性有关。本文综述了神经化学检测，受体密度研究，神经内分泌挑战范式，功能性神经影像学研究和候选基因研究，这些研究旨在确定边缘型人格障碍患者中似乎失调的特定神经递质系统。
Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability. This article reviews evidence from neurochemical assays, receptor-density studies, neuroendocrine-challenge paradigms, functional neuroimaging studies, and candidate-gene research, which converge to identify particular neurotransmitter systems that seem to be dysregulated in patients with borderline personality disorder.