The metabolic syndrome - Prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
The metabolic syndrome - Prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
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DOI：
10.1001/archinte.163.4.427
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发表时间：
2003-02-24
影响因子：
--
通讯作者：
Heymsfield, SB
中科院分区：
文献类型：
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作者：
Park, YW;Zhu, SK;Heymsfield, SB
背景：代谢综合征是冠心病的一组重要危险因素，常见的有胰岛素抵抗。在美国人群中，代谢综合征与人口统计学和潜在可改变的生活方式因素的相关程度尚不清楚。根据成人治疗组III标准的定义，在3305名黑人、3477名墨西哥裔美国人、和5581名年龄在20岁及以上的白色男性和非妊娠或哺乳期女性参与了第三次全国健康与营养检查调查。美国男性和女性的代谢综合征患病率分别为22.8%和22.6%（P= 0.86）。特定年龄的患病率在墨西哥裔美国人中最高，在黑人中最低。即使在调整了年龄、体重指数和社会经济地位之后，种族差异仍然存在。在正常体重、超重和肥胖男性中，代谢综合征的发生率分别为4.6%、22.4%和59.6%，在女性中也观察到类似的分布。年龄较大，绝经后状态，墨西哥裔美国人，较高的身体质量指数，目前吸烟，低家庭收入，高碳水化合物的摄入量，没有酒精的消费，和身体不活动与增加的几率的代谢syndrome.Conclusions：代谢综合征是目前在超过20%的美国成年人口;即使在调整体重指数、年龄、社会经济地位和其他预测变量后，种族差异也很大;并且与几个潜在的可改变的生活方式因素相关。对这一高危人群的识别和临床管理是冠心病预防的一个重要方面。
Background: The metabolic syndrome is an important cluster of coronary heart disease risk factors with common insulin resistance. The extent to which the metabolic syndrome is associated with demographic and potentially modifiable lifestyle factors in the US population is unknown.Methods: Metabolic syndrome-associated factors and prevalence, as defined by Adult Treatment Panel III criteria, were evaluated in a representative US sample of 3305 black, 3477 Mexican American, and 5581 white men and nonpregnant or lactating women aged 20 years and older who participated in the cross-sectional Third National Health and Nutrition Examination Survey.Results: The metabolic syndrome was present in 22.8% and 22.6% of US men and women, respectively (P=.86). The age-specific prevalence was highest in Mexican Americans and lowest in blacks of both sexes. Ethnic differences persisted even after adjusting for age, body mass index, and socioeconomic status. The metabolic syndrome was present in 4.6%, 22.4%, and 59.6% of normal-weight, overweight, and obese men, respectively, and a similar distribution was observed in women. Older age, postmenopausal status, Mexican American ethnicity, higher body mass index, current smoking, low household income, high carbohydrate intake, no alcohol consumption, and physical inactivity were associated with increased odds of the metabolic syndrome.Conclusions: The metabolic syndrome is present in more than 20% of the US adult population; varies substantially by ethnicity even after adjusting for body mass index, age, socioeconomic status, and other predictor variables; and is associated with several potentially modifiable lifestyle factors. Identification and clinical management of this high-risk group is an important aspect of coronary heart disease prevention.