Treatment of nonmetastatic and metastatic low-risk gestational trophoblastic neoplasia: Factors associated with resistance to single-agent methotrexate chemotherapy

Treatment of nonmetastatic and metastatic low-risk gestational trophoblastic neoplasia: Factors associated with resistance to single-agent methotrexate chemotherapy
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DOI:
10.1016/j.ygyno.2012.03.039
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发表时间:
2012-06-01
影响因子:
4.7
通讯作者:
Lurain, John R.
Lurain, John R.
中科院分区:
医学2区
文献类型:
--
作者:
Chapman-Davis, Eloise;Hoekstra, Anna V.;Lurain, John R.

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目标。目的:探讨甲氨蝶呤治疗低危妊娠滋养细胞瘤(GTN)耐药的相关因素。我们回顾了358例低风险GTN (FIGO I期和II-III期评分)患者的记录
Objective. To determine factors associated with resistance to methotrexate treatment of low-risk gestational trophoblastic neoplasia (GTN).Methods. We reviewed the records of 358 patients with low-risk GTN (FIGO stage I and stages II-III score